Deletion of the angiotensin II type 1 receptor–associated protein enhances renal sodium reabsorption and exacerbates angiotensin II–mediated hypertension

Angiotensin II type 1 receptor (AT1R)–associated protein (ATRAP) promotes AT1R internalization along with suppression of pathological activation of tissue AT1R signaling. However, the functional significance of ATRAP in renal sodium handling and blood pressure regulation under pathological stimuli i...

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Detalles Bibliográficos
Autores principales: Ohsawa, Masato, Tamura, Kouichi, Wakui, Hiromichi, Maeda, Akinobu, Dejima, Toru, Kanaoka, Tomohiko, Azushima, Kengo, Uneda, Kazushi, Tsurumi-Ikeya, Yuko, Kobayashi, Ryu, Matsuda, Miyuki, Uchida, Shinichi, Toya, Yoshiyuki, Kobori, Hiroyuki, Nishiyama, Akira, Yamashita, Akio, Ishikawa, Yoshihiro, Umemura, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149871/
https://www.ncbi.nlm.nih.gov/pubmed/24694992
http://dx.doi.org/10.1038/ki.2014.95

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