Activation of a TRP-like channel and intracellular Ca(2+) dynamics during phospholipase-C-mediated cell death

The model organism Neurospora crassa undergoes programmed cell death when exposed to staurosporine. Here, we show that staurosporine causes defined changes in cytosolic free Ca(2+) ([Ca(2+)](c)) dynamics and a distinct Ca(2+) signature that involves Ca(2+) influx from the external medium and interna...

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Detalles Bibliográficos
Autores principales: Gonçalves, A. Pedro, Cordeiro, J. Miguel, Monteiro, João, Muñoz, Alberto, Correia-de-Sá, Paulo, Read, Nick D., Videira, Arnaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150065/
https://www.ncbi.nlm.nih.gov/pubmed/25037570
http://dx.doi.org/10.1242/jcs.152058

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