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Phagosome maturation during endosome interaction revealed by partial rhodopsin processing in retinal pigment epithelium

Defects in phagocytosis and degradation of photoreceptor outer segments (POS) by the retinal pigment epithelium (RPE) are associated with aging and retinal disease. The daily burst of rod outer segment (ROS) phagocytosis by the RPE provides a unique opportunity to analyse phagosome processing in viv...

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Detalles Bibliográficos
Autores principales: Wavre-Shapton, Silène T., Meschede, Ingrid P., Seabra, Miguel C., Futter, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150067/
https://www.ncbi.nlm.nih.gov/pubmed/25074813
http://dx.doi.org/10.1242/jcs.154757