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Medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter?
BACKGROUND: The simultaneous use of several medications is an important risk factor for injurious falls in older people. The aim of this study is to investigate the effect of the number of medications dispensed to elderly persons on fall injuries and to assess whether this relationship is explained...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150120/ https://www.ncbi.nlm.nih.gov/pubmed/25151122 http://dx.doi.org/10.1186/1471-2318-14-92 |
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author | Helgadóttir, Björg Laflamme, Lucie Monárrez-Espino, Joel Möller, Jette |
author_facet | Helgadóttir, Björg Laflamme, Lucie Monárrez-Espino, Joel Möller, Jette |
author_sort | Helgadóttir, Björg |
collection | PubMed |
description | BACKGROUND: The simultaneous use of several medications is an important risk factor for injurious falls in older people. The aim of this study is to investigate the effect of the number of medications dispensed to elderly persons on fall injuries and to assess whether this relationship is explained by individual demographics, health habits and health status. METHODS: A population-based, nested, case–control study on people 65 years and older (N = 20.906) was conducted using data from the Stockholm Public Health Cohort (SPHC) derived from self-administered surveys and linked at the individual level with various Swedish health registers. Fall injuries leading to hospitalization recorded in the Swedish National Patient Register (NPR) were considered as the outcome. The main exposure, obtained from the Swedish Prescribed Drug Register (SPDR), was the number of medications dispensed within 90 days prior to the injurious fall. The injury risk was estimated using adjusted odds ratios (ORs) from logistic regression. Results were adjusted by selected demographic, social circumstances, lifestyle and health status data extracted from the SPHC. RESULTS: After adjusting for common risk factors within demographics, lifestyle, social circumstances and health status, using more than one medication increased the risk of fall injury but no clear dose–response relationship was observed, with point estimates ranging from 1.5-1.7 for the use of two, three, four or five or more medications as compared to using none. An increased risk remained, and was even elevated, after adjusting for the use of fall-risk-increasing drugs (FRIDs). CONCLUSIONS: Using more than one medication affects the risk of injurious falls among older people. The effect of any given number of medications studied remains and is even strengthened after adjusting for individual demographics, health habits, health conditions and the use of FRIDs. |
format | Online Article Text |
id | pubmed-4150120 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-41501202014-09-02 Medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter? Helgadóttir, Björg Laflamme, Lucie Monárrez-Espino, Joel Möller, Jette BMC Geriatr Research Article BACKGROUND: The simultaneous use of several medications is an important risk factor for injurious falls in older people. The aim of this study is to investigate the effect of the number of medications dispensed to elderly persons on fall injuries and to assess whether this relationship is explained by individual demographics, health habits and health status. METHODS: A population-based, nested, case–control study on people 65 years and older (N = 20.906) was conducted using data from the Stockholm Public Health Cohort (SPHC) derived from self-administered surveys and linked at the individual level with various Swedish health registers. Fall injuries leading to hospitalization recorded in the Swedish National Patient Register (NPR) were considered as the outcome. The main exposure, obtained from the Swedish Prescribed Drug Register (SPDR), was the number of medications dispensed within 90 days prior to the injurious fall. The injury risk was estimated using adjusted odds ratios (ORs) from logistic regression. Results were adjusted by selected demographic, social circumstances, lifestyle and health status data extracted from the SPHC. RESULTS: After adjusting for common risk factors within demographics, lifestyle, social circumstances and health status, using more than one medication increased the risk of fall injury but no clear dose–response relationship was observed, with point estimates ranging from 1.5-1.7 for the use of two, three, four or five or more medications as compared to using none. An increased risk remained, and was even elevated, after adjusting for the use of fall-risk-increasing drugs (FRIDs). CONCLUSIONS: Using more than one medication affects the risk of injurious falls among older people. The effect of any given number of medications studied remains and is even strengthened after adjusting for individual demographics, health habits, health conditions and the use of FRIDs. BioMed Central 2014-08-23 /pmc/articles/PMC4150120/ /pubmed/25151122 http://dx.doi.org/10.1186/1471-2318-14-92 Text en Copyright © 2014 Helgadóttir et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Helgadóttir, Björg Laflamme, Lucie Monárrez-Espino, Joel Möller, Jette Medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter? |
title | Medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter? |
title_full | Medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter? |
title_fullStr | Medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter? |
title_full_unstemmed | Medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter? |
title_short | Medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter? |
title_sort | medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter? |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150120/ https://www.ncbi.nlm.nih.gov/pubmed/25151122 http://dx.doi.org/10.1186/1471-2318-14-92 |
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