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OMICS: Current and future perspectives in reproductive medicine and technology
Many couples present fertility problems at their reproductive age, and although in the last years, the efficiency of assisted reproduction techniques has increased, these are still far from being 100% effective. A key issue in this field is the proper assessment of germ cells, embryos and endometriu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150148/ https://www.ncbi.nlm.nih.gov/pubmed/25191020 http://dx.doi.org/10.4103/0974-1208.138857 |
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author | Egea, Rocío Rivera Puchalt, Nicolás Garrido Escrivá, Marcos Meseguer Varghese, Alex C. |
author_facet | Egea, Rocío Rivera Puchalt, Nicolás Garrido Escrivá, Marcos Meseguer Varghese, Alex C. |
author_sort | Egea, Rocío Rivera |
collection | PubMed |
description | Many couples present fertility problems at their reproductive age, and although in the last years, the efficiency of assisted reproduction techniques has increased, these are still far from being 100% effective. A key issue in this field is the proper assessment of germ cells, embryos and endometrium quality, in order to determine the actual likelihood to succeed. Currently available analysis is mainly based on morphological features of oocytes, sperm and embryos and although these strategies have improved the results, there is an urgent need of new diagnostic and therapeutic tools. The emergence of the - OMICS technologies (epigenomics, genomics, transcriptomics, proteomics and metabolomics) permitted the improvement on the knowledge in this field, by providing with a huge amount of information regarding the biological processes involved in reproductive success, thereby getting a broader view of complex biological systems with a relatively low cost and effort. |
format | Online Article Text |
id | pubmed-4150148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-41501482014-09-04 OMICS: Current and future perspectives in reproductive medicine and technology Egea, Rocío Rivera Puchalt, Nicolás Garrido Escrivá, Marcos Meseguer Varghese, Alex C. J Hum Reprod Sci Review Article Many couples present fertility problems at their reproductive age, and although in the last years, the efficiency of assisted reproduction techniques has increased, these are still far from being 100% effective. A key issue in this field is the proper assessment of germ cells, embryos and endometrium quality, in order to determine the actual likelihood to succeed. Currently available analysis is mainly based on morphological features of oocytes, sperm and embryos and although these strategies have improved the results, there is an urgent need of new diagnostic and therapeutic tools. The emergence of the - OMICS technologies (epigenomics, genomics, transcriptomics, proteomics and metabolomics) permitted the improvement on the knowledge in this field, by providing with a huge amount of information regarding the biological processes involved in reproductive success, thereby getting a broader view of complex biological systems with a relatively low cost and effort. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4150148/ /pubmed/25191020 http://dx.doi.org/10.4103/0974-1208.138857 Text en Copyright: © Journal of Human Reproductive Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Egea, Rocío Rivera Puchalt, Nicolás Garrido Escrivá, Marcos Meseguer Varghese, Alex C. OMICS: Current and future perspectives in reproductive medicine and technology |
title | OMICS: Current and future perspectives in reproductive medicine and technology |
title_full | OMICS: Current and future perspectives in reproductive medicine and technology |
title_fullStr | OMICS: Current and future perspectives in reproductive medicine and technology |
title_full_unstemmed | OMICS: Current and future perspectives in reproductive medicine and technology |
title_short | OMICS: Current and future perspectives in reproductive medicine and technology |
title_sort | omics: current and future perspectives in reproductive medicine and technology |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150148/ https://www.ncbi.nlm.nih.gov/pubmed/25191020 http://dx.doi.org/10.4103/0974-1208.138857 |
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