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OMICS: Current and future perspectives in reproductive medicine and technology

Many couples present fertility problems at their reproductive age, and although in the last years, the efficiency of assisted reproduction techniques has increased, these are still far from being 100% effective. A key issue in this field is the proper assessment of germ cells, embryos and endometriu...

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Detalles Bibliográficos
Autores principales: Egea, Rocío Rivera, Puchalt, Nicolás Garrido, Escrivá, Marcos Meseguer, Varghese, Alex C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150148/
https://www.ncbi.nlm.nih.gov/pubmed/25191020
http://dx.doi.org/10.4103/0974-1208.138857
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author Egea, Rocío Rivera
Puchalt, Nicolás Garrido
Escrivá, Marcos Meseguer
Varghese, Alex C.
author_facet Egea, Rocío Rivera
Puchalt, Nicolás Garrido
Escrivá, Marcos Meseguer
Varghese, Alex C.
author_sort Egea, Rocío Rivera
collection PubMed
description Many couples present fertility problems at their reproductive age, and although in the last years, the efficiency of assisted reproduction techniques has increased, these are still far from being 100% effective. A key issue in this field is the proper assessment of germ cells, embryos and endometrium quality, in order to determine the actual likelihood to succeed. Currently available analysis is mainly based on morphological features of oocytes, sperm and embryos and although these strategies have improved the results, there is an urgent need of new diagnostic and therapeutic tools. The emergence of the - OMICS technologies (epigenomics, genomics, transcriptomics, proteomics and metabolomics) permitted the improvement on the knowledge in this field, by providing with a huge amount of information regarding the biological processes involved in reproductive success, thereby getting a broader view of complex biological systems with a relatively low cost and effort.
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spelling pubmed-41501482014-09-04 OMICS: Current and future perspectives in reproductive medicine and technology Egea, Rocío Rivera Puchalt, Nicolás Garrido Escrivá, Marcos Meseguer Varghese, Alex C. J Hum Reprod Sci Review Article Many couples present fertility problems at their reproductive age, and although in the last years, the efficiency of assisted reproduction techniques has increased, these are still far from being 100% effective. A key issue in this field is the proper assessment of germ cells, embryos and endometrium quality, in order to determine the actual likelihood to succeed. Currently available analysis is mainly based on morphological features of oocytes, sperm and embryos and although these strategies have improved the results, there is an urgent need of new diagnostic and therapeutic tools. The emergence of the - OMICS technologies (epigenomics, genomics, transcriptomics, proteomics and metabolomics) permitted the improvement on the knowledge in this field, by providing with a huge amount of information regarding the biological processes involved in reproductive success, thereby getting a broader view of complex biological systems with a relatively low cost and effort. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4150148/ /pubmed/25191020 http://dx.doi.org/10.4103/0974-1208.138857 Text en Copyright: © Journal of Human Reproductive Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Egea, Rocío Rivera
Puchalt, Nicolás Garrido
Escrivá, Marcos Meseguer
Varghese, Alex C.
OMICS: Current and future perspectives in reproductive medicine and technology
title OMICS: Current and future perspectives in reproductive medicine and technology
title_full OMICS: Current and future perspectives in reproductive medicine and technology
title_fullStr OMICS: Current and future perspectives in reproductive medicine and technology
title_full_unstemmed OMICS: Current and future perspectives in reproductive medicine and technology
title_short OMICS: Current and future perspectives in reproductive medicine and technology
title_sort omics: current and future perspectives in reproductive medicine and technology
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150148/
https://www.ncbi.nlm.nih.gov/pubmed/25191020
http://dx.doi.org/10.4103/0974-1208.138857
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