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Selective CREB-dependent cyclin expression mediated by the PI3K and MAPK pathways supports glioma cell proliferation
The cyclic-AMP response element binding (CREB) protein has been shown to have a pivotal role in cell survival and cell proliferation. Transgenic rodent models have revealed a role for CREB in higher-order brain functions, such as memory and drug addiction behaviors. CREB overexpression in transgenic...
Autores principales: | Daniel, P, Filiz, G, Brown, D V, Hollande, F, Gonzales, M, D'Abaco, G, Papalexis, N, Phillips, W A, Malaterre, J, Ramsay, R G, Mantamadiotis, T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150215/ https://www.ncbi.nlm.nih.gov/pubmed/24979279 http://dx.doi.org/10.1038/oncsis.2014.21 |
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