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Emergence of human babesiosis along the border of China with Myanmar: detection by PCR and confirmation by sequencing

Babesiosis is a tick-borne, zoonotic disease caused by Babesia spp. Two cases of babesiosis were detected by nested polymerase chain reaction (PCR) in Yunnan province, China, and further confirmed by molecular assay. The blood smears showed intraerythrocytic ring form and tetrads typical of small B....

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Autores principales: Zhou, Xia, Li, Sheng-Guo, Wang, Jia-Zhi, Huang, Ji-lei, Zhou, He-Jun, Chen, Jun-Hu, Zhou, Xiao-Nong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150284/
https://www.ncbi.nlm.nih.gov/pubmed/26038750
http://dx.doi.org/10.1038/emi.2014.55
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author Zhou, Xia
Li, Sheng-Guo
Wang, Jia-Zhi
Huang, Ji-lei
Zhou, He-Jun
Chen, Jun-Hu
Zhou, Xiao-Nong
author_facet Zhou, Xia
Li, Sheng-Guo
Wang, Jia-Zhi
Huang, Ji-lei
Zhou, He-Jun
Chen, Jun-Hu
Zhou, Xiao-Nong
author_sort Zhou, Xia
collection PubMed
description Babesiosis is a tick-borne, zoonotic disease caused by Babesia spp. Two cases of babesiosis were detected by nested polymerase chain reaction (PCR) in Yunnan province, China, and further confirmed by molecular assay. The blood smears showed intraerythrocytic ring form and tetrads typical of small B. microti. In both cases, the rapid diagnostic test (RDT) ruled out the possibility of co-infections with malaria. Neither case was initially diagnosed because of the low Babesia parasitemia. These two cases of babesiosis in areas along the Myanmar–China border pose the question of the emergence of this under recognized infection in countries or areas where malaria is endemic.
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spelling pubmed-41502842014-09-03 Emergence of human babesiosis along the border of China with Myanmar: detection by PCR and confirmation by sequencing Zhou, Xia Li, Sheng-Guo Wang, Jia-Zhi Huang, Ji-lei Zhou, He-Jun Chen, Jun-Hu Zhou, Xiao-Nong Emerg Microbes Infect Case Report Babesiosis is a tick-borne, zoonotic disease caused by Babesia spp. Two cases of babesiosis were detected by nested polymerase chain reaction (PCR) in Yunnan province, China, and further confirmed by molecular assay. The blood smears showed intraerythrocytic ring form and tetrads typical of small B. microti. In both cases, the rapid diagnostic test (RDT) ruled out the possibility of co-infections with malaria. Neither case was initially diagnosed because of the low Babesia parasitemia. These two cases of babesiosis in areas along the Myanmar–China border pose the question of the emergence of this under recognized infection in countries or areas where malaria is endemic. Nature Publishing Group 2014-08 2014-08-06 /pmc/articles/PMC4150284/ /pubmed/26038750 http://dx.doi.org/10.1038/emi.2014.55 Text en Copyright © 2014 Shanghai Shangyixun Cultural Communication Co., Ltd http://creativecommons.org/licenses/by-nc-sa/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permissing from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Case Report
Zhou, Xia
Li, Sheng-Guo
Wang, Jia-Zhi
Huang, Ji-lei
Zhou, He-Jun
Chen, Jun-Hu
Zhou, Xiao-Nong
Emergence of human babesiosis along the border of China with Myanmar: detection by PCR and confirmation by sequencing
title Emergence of human babesiosis along the border of China with Myanmar: detection by PCR and confirmation by sequencing
title_full Emergence of human babesiosis along the border of China with Myanmar: detection by PCR and confirmation by sequencing
title_fullStr Emergence of human babesiosis along the border of China with Myanmar: detection by PCR and confirmation by sequencing
title_full_unstemmed Emergence of human babesiosis along the border of China with Myanmar: detection by PCR and confirmation by sequencing
title_short Emergence of human babesiosis along the border of China with Myanmar: detection by PCR and confirmation by sequencing
title_sort emergence of human babesiosis along the border of china with myanmar: detection by pcr and confirmation by sequencing
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150284/
https://www.ncbi.nlm.nih.gov/pubmed/26038750
http://dx.doi.org/10.1038/emi.2014.55
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