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Lipomatous pleomorphic adenoma in the hard palate: Report of a rare case with cyto-histo correlation and review

Pleomorphic adenoma is the most common benign tumor of the salivary glands. They are usually composed of epithelial/myoepithelial cells and chondromyxoid stroma. Extensive lipomatous differentiation is very rare. We report a case of lipomatous pleomorphic adenoma (LPA) that presented with a mass in...

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Autores principales: Musayev, Jamal, Önal, Binnur, Hasanov, Adalat, Farzaliyev, Ismayil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150340/
https://www.ncbi.nlm.nih.gov/pubmed/25190982
http://dx.doi.org/10.4103/0970-9371.130689
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author Musayev, Jamal
Önal, Binnur
Hasanov, Adalat
Farzaliyev, Ismayil
author_facet Musayev, Jamal
Önal, Binnur
Hasanov, Adalat
Farzaliyev, Ismayil
author_sort Musayev, Jamal
collection PubMed
description Pleomorphic adenoma is the most common benign tumor of the salivary glands. They are usually composed of epithelial/myoepithelial cells and chondromyxoid stroma. Extensive lipomatous differentiation is very rare. We report a case of lipomatous pleomorphic adenoma (LPA) that presented with a mass in the hard palate of a 32-year-old woman. The fine-needle aspiration cytology material was reported as benign cytology consistent with adenoma with major adipocytic component. Histopathological examination of the excision material displayed that more than 90% of the tumor was adipocytic in texture, containing scant epithelial and myoepithelial cells and chondromyxoid stromal fragments. Preoperative cytodiagnosis of lipomatous pleomorphic adenoma on FNA is based on cytomorphology intimately associated pleomorphic adenomatous and lipomatous tissue elements. LPA should be on the mental list of the (cyto)pathologist in differential diagnosis of lipomatous tumors or non-tumorous lipomatosis or carcinoma invasion in the adipose tissue of the minor salivary gland of the hard palate.
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spelling pubmed-41503402014-09-04 Lipomatous pleomorphic adenoma in the hard palate: Report of a rare case with cyto-histo correlation and review Musayev, Jamal Önal, Binnur Hasanov, Adalat Farzaliyev, Ismayil J Cytol Case Report Pleomorphic adenoma is the most common benign tumor of the salivary glands. They are usually composed of epithelial/myoepithelial cells and chondromyxoid stroma. Extensive lipomatous differentiation is very rare. We report a case of lipomatous pleomorphic adenoma (LPA) that presented with a mass in the hard palate of a 32-year-old woman. The fine-needle aspiration cytology material was reported as benign cytology consistent with adenoma with major adipocytic component. Histopathological examination of the excision material displayed that more than 90% of the tumor was adipocytic in texture, containing scant epithelial and myoepithelial cells and chondromyxoid stromal fragments. Preoperative cytodiagnosis of lipomatous pleomorphic adenoma on FNA is based on cytomorphology intimately associated pleomorphic adenomatous and lipomatous tissue elements. LPA should be on the mental list of the (cyto)pathologist in differential diagnosis of lipomatous tumors or non-tumorous lipomatosis or carcinoma invasion in the adipose tissue of the minor salivary gland of the hard palate. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4150340/ /pubmed/25190982 http://dx.doi.org/10.4103/0970-9371.130689 Text en Copyright: © Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Musayev, Jamal
Önal, Binnur
Hasanov, Adalat
Farzaliyev, Ismayil
Lipomatous pleomorphic adenoma in the hard palate: Report of a rare case with cyto-histo correlation and review
title Lipomatous pleomorphic adenoma in the hard palate: Report of a rare case with cyto-histo correlation and review
title_full Lipomatous pleomorphic adenoma in the hard palate: Report of a rare case with cyto-histo correlation and review
title_fullStr Lipomatous pleomorphic adenoma in the hard palate: Report of a rare case with cyto-histo correlation and review
title_full_unstemmed Lipomatous pleomorphic adenoma in the hard palate: Report of a rare case with cyto-histo correlation and review
title_short Lipomatous pleomorphic adenoma in the hard palate: Report of a rare case with cyto-histo correlation and review
title_sort lipomatous pleomorphic adenoma in the hard palate: report of a rare case with cyto-histo correlation and review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150340/
https://www.ncbi.nlm.nih.gov/pubmed/25190982
http://dx.doi.org/10.4103/0970-9371.130689
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