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Cyclin-dependent kinase 5, a node protein in diminished tauopathy: a systems biology approach

Alzheimer's disease (AD) is the most common cause of dementia worldwide. One of the main pathological changes that occurs in AD is the intracellular accumulation of hyperphosphorylated Tau protein in neurons. Cyclin-dependent kinase 5 (CDK5) is one of the major kinases involved in Tau phosphory...

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Detalles Bibliográficos
Autores principales:	Castro-Alvarez, John F., Uribe-Arias, S. Alejandro, Mejía-Raigosa, Daniel, Cardona-Gómez, Gloria P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150361/ https://www.ncbi.nlm.nih.gov/pubmed/25225483 http://dx.doi.org/10.3389/fnagi.2014.00232

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