Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents

The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics ass...

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Detalles Bibliográficos
Autores principales: El-Sherif, Ahmed A., Shoukry, Mohamed M., Abd Elkarim, Abeer T., Barakat, Mohammad H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150405/
https://www.ncbi.nlm.nih.gov/pubmed/25197267
http://dx.doi.org/10.1155/2014/626719
Descripción
Sumario:The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics associated with protonation equilibria were also discussed.

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