Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents

The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics ass...

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Detalles Bibliográficos
Autores principales: El-Sherif, Ahmed A., Shoukry, Mohamed M., Abd Elkarim, Abeer T., Barakat, Mohammad H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150405/
https://www.ncbi.nlm.nih.gov/pubmed/25197267
http://dx.doi.org/10.1155/2014/626719
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author El-Sherif, Ahmed A.
Shoukry, Mohamed M.
Abd Elkarim, Abeer T.
Barakat, Mohammad H.
author_facet El-Sherif, Ahmed A.
Shoukry, Mohamed M.
Abd Elkarim, Abeer T.
Barakat, Mohammad H.
author_sort El-Sherif, Ahmed A.
collection PubMed
description The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics associated with protonation equilibria were also discussed.
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spelling pubmed-41504052014-09-07 Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents El-Sherif, Ahmed A. Shoukry, Mohamed M. Abd Elkarim, Abeer T. Barakat, Mohammad H. Bioinorg Chem Appl Review Article The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics associated with protonation equilibria were also discussed. Hindawi Publishing Corporation 2014 2014-08-14 /pmc/articles/PMC4150405/ /pubmed/25197267 http://dx.doi.org/10.1155/2014/626719 Text en Copyright © 2014 Ahmed A. El-Sherif et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
El-Sherif, Ahmed A.
Shoukry, Mohamed M.
Abd Elkarim, Abeer T.
Barakat, Mohammad H.
Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title_full Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title_fullStr Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title_full_unstemmed Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title_short Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title_sort protonation equilibria of biologically active ligands in mixed aqueous organic solvents
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150405/
https://www.ncbi.nlm.nih.gov/pubmed/25197267
http://dx.doi.org/10.1155/2014/626719
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