Cargando…

Proteomic Analysis of Gossypol Induces Necrosis in Multiple Myeloma Cells

Gossypol is a phenolic aldehyde extracted from plants and is known to be an antitumor agent to induce cancer cell apoptosis. In the present study, multiple myeloma cells were treated with gossypol, which resulted in an increase of cellular reactive oxygen species (ROS) and cell necrosis. Quantitativ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Renhua, Tian, Enbing, Tang, Haiping, Liu, Chongdong, Wang, Qingtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150408/ https://www.ncbi.nlm.nih.gov/pubmed/25197664 http://dx.doi.org/10.1155/2014/839232

Ejemplares similares

Azacytidine induces necrosis of multiple myeloma cells through oxidative stress
por: Tian, Enbing, et al.
Publicado: (2013)

Oxidative Stress Induces Monocyte Necrosis with Enrichment of Cell-Bound Albumin and Overexpression of Endoplasmic Reticulum and Mitochondrial Chaperones
por: Tang, Haiping, et al.
Publicado: (2013)

Induction of multiple subroutines of regulated necrosis in murine macrophages by natural BH3-mimetic gossypol: Induction of regulated necrosis in macrophages by gossypol
por: Zhong, Meiyan, et al.
Publicado: (2021)

Gossypol induces apoptosis in multiple myeloma cells by inhibition of interleukin-6 signaling and Bcl-2/Mcl-1 pathway
por: SADAHIRA, KEN, et al.
Publicado: (2014)

Characterization of gossypol biosynthetic pathway
por: Tian, Xiu, et al.
Publicado: (2018)

Cytotoxicity of enantiomers of gossypol.
por: Joseph, A. E., et al.
Publicado: (1986)

Proteomic Analysis of eIF5B Silencing-Modulated Proteostasis
por: Jiang, Xu, et al.
Publicado: (2016)

Gossypol-Induced Differentiation in Human Leukemia HL-60 Cells
por: Wang, Wen-Qing, et al.
Publicado: (2006)

Biodegradation of Gossypol by Aspergillus terreus-YJ01
por: Jiang, Yao, et al.
Publicado: (2023)

Development of the Fc-III Tagged Protein Expression System for Protein Purification and Detection
por: Feng, Shan, et al.
Publicado: (2012)

Gossypol Toxicity from Cottonseed Products
por: Gadelha, Ivana Cristina N., et al.
Publicado: (2014)

Presence of free gossypol in whole cottonseed
por: Knutsen, Helle Katrine, et al.
Publicado: (2017)

Intramolecular Annulation of Gossypol by Laccase to Produce Safe Cottonseed Protein
por: Wang, Lin, et al.
Publicado: (2020)

Protective effect of gossypol on lipopolysaccharide-induced acute lung injury in mice
por: Liu, Zhicheng, et al.
Publicado: (2013)

Gossypol Promotes Bone Formation in Ovariectomy-Induced Osteoporosis through Regulating Cell Apoptosis
por: Liang, Jinqian, et al.
Publicado: (2018)

Gossypol Promotes Degeneration of Ovarian Follicles in Rats
por: Gadelha, Ivana Cristina Nunes, et al.
Publicado: (2014)

Redetermined structure of gossypol (P3 polymorph)
por: Honkeldieva, Muhabbat, et al.
Publicado: (2015)

Prenatal Exposure to Gossypol Impairs Corticogenesis of Mouse
por: Zhu, Xiaoyan, et al.
Publicado: (2020)

Phosphoproteomic Analysis of Gossypol-Induced Apoptosis in Ovarian Cancer Cell Line, HOC1a
por: Jin, Lixu, et al.
Publicado: (2014)

A gossypol biosynthetic intermediate disturbs plant defence response
por: Tian, Xiu, et al.
Publicado: (2019)

Investigating Stability and Tautomerization of Gossypol—A Spectroscopy Study
por: Wang, Lulu, et al.
Publicado: (2019)

Gestational and lactational exposure to gossypol alters the testis transcriptome
por: Louvandini, Helder, et al.
Publicado: (2020)

Cotton roots are the major source of gossypol biosynthesis and accumulation
por: Zhao, Tianlun, et al.
Publicado: (2020)

Systematic Review of Gossypol/AT-101 in Cancer Clinical Trials
por: Renner, Olga, et al.
Publicado: (2022)

New function of gossypol, a natural product of cotton
por: Huang, Jinquan, et al.
Publicado: (2022)

Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol
por: Judge, Jennifer L., et al.
Publicado: (2018)

Multiple myeloma characterized by synovial fibrinoid necrosis: a case report
por: Liu, You jun, et al.
Publicado: (2021)

Proteomic Analysis for Finding Serum Pathogenic Factors and Potential Biomarkers in Multiple Myeloma
por: Zhang, Hong-Tao, et al.
Publicado: (2015)

Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells
por: Yuan, Y, et al.
Publicado: (2013)

Gossypol Promotes Wnt/β-Catenin Signaling through WIF1 in Ovariectomy-Induced Osteoporosis
por: Liang, Jinqian, et al.
Publicado: (2019)

Proteomics Analysis for Finding Serum Markers of Ovarian Cancer
por: Cheng, Yushan, et al.
Publicado: (2014)

Transcriptome analysis reveals the effect of grafting on gossypol biosynthesis and gland formation in cotton
por: Ye, Kun, et al.
Publicado: (2023)

Plant Polyphenol Gossypol Induced Cell Death and Its Association with Gene Expression in Mouse Macrophages
por: Cao, Heping, et al.
Publicado: (2023)

Constitutive and induced insect resistance in RNAi-mediated ultra-low gossypol cottonseed cotton
por: Hagenbucher, Steffen, et al.
Publicado: (2019)

Toxicity of Gossypol from Cottonseed Cake to Sheep Ovarian Follicles
por: Câmara, Antônio Carlos Lopes, et al.
Publicado: (2015)

Gossypol Content of Cotton Free Commercial Feed for Dairy Cows
por: Ricci, Barbara, et al.
Publicado: (2015)

Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres
por: Kim, Hee Yeon, et al.
Publicado: (2019)

Gossypol detoxification in the rumen and Helicoverpa armigera larvae: A review
por: Wang, Wei-Kang, et al.
Publicado: (2021)

The reversible effects of gossypol toxicity on male pigeons’ reproductive performance
por: Wannaratana, Suwarak, et al.
Publicado: (2022)

Gossypol Broadly Inhibits Coronaviruses by Targeting RNA‐Dependent RNA Polymerases
por: Wang, Wenjing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m8ivjvsusd6b0g6j8ebunugi98