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Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae

Volatile energy costs and environmental concerns have spurred interest in the development of alternative, renewable, sustainable, and cost-effective energy resources. Environment-friendly processes involving microbes can be used to synthesize advanced biofuels. These fuels have the potential to repl...

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Autores principales: Zhou, Yongjin J., Buijs, Nicolaas A., Siewers, Verena, Nielsen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150446/
https://www.ncbi.nlm.nih.gov/pubmed/25225637
http://dx.doi.org/10.3389/fbioe.2014.00032
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author Zhou, Yongjin J.
Buijs, Nicolaas A.
Siewers, Verena
Nielsen, Jens
author_facet Zhou, Yongjin J.
Buijs, Nicolaas A.
Siewers, Verena
Nielsen, Jens
author_sort Zhou, Yongjin J.
collection PubMed
description Volatile energy costs and environmental concerns have spurred interest in the development of alternative, renewable, sustainable, and cost-effective energy resources. Environment-friendly processes involving microbes can be used to synthesize advanced biofuels. These fuels have the potential to replace fossil fuels in supporting high-power demanding machinery such as aircrafts and trucks. From an engineering perspective, the pathway for fatty acid biosynthesis is an attractive route for the production of advanced fuels such as fatty acid ethyl esters, fatty alcohols, and alkanes. The robustness and excellent accessibility to molecular genetics make the yeast Saccharomyces cerevisiae a suitable host for the purpose of bio-manufacturing. Recent advances in metabolic engineering, as well as systems and synthetic biology, have now provided the opportunity to engineer yeast metabolism for the production of fatty acid-derived fuels and chemicals.
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spelling pubmed-41504462014-09-15 Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae Zhou, Yongjin J. Buijs, Nicolaas A. Siewers, Verena Nielsen, Jens Front Bioeng Biotechnol Bioengineering and Biotechnology Volatile energy costs and environmental concerns have spurred interest in the development of alternative, renewable, sustainable, and cost-effective energy resources. Environment-friendly processes involving microbes can be used to synthesize advanced biofuels. These fuels have the potential to replace fossil fuels in supporting high-power demanding machinery such as aircrafts and trucks. From an engineering perspective, the pathway for fatty acid biosynthesis is an attractive route for the production of advanced fuels such as fatty acid ethyl esters, fatty alcohols, and alkanes. The robustness and excellent accessibility to molecular genetics make the yeast Saccharomyces cerevisiae a suitable host for the purpose of bio-manufacturing. Recent advances in metabolic engineering, as well as systems and synthetic biology, have now provided the opportunity to engineer yeast metabolism for the production of fatty acid-derived fuels and chemicals. Frontiers Media S.A. 2014-09-01 /pmc/articles/PMC4150446/ /pubmed/25225637 http://dx.doi.org/10.3389/fbioe.2014.00032 Text en Copyright © 2014 Zhou, Buijs, Siewers and Nielsen. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Zhou, Yongjin J.
Buijs, Nicolaas A.
Siewers, Verena
Nielsen, Jens
Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae
title Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae
title_full Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae
title_fullStr Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae
title_full_unstemmed Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae
title_short Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae
title_sort fatty acid-derived biofuels and chemicals production in saccharomyces cerevisiae
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150446/
https://www.ncbi.nlm.nih.gov/pubmed/25225637
http://dx.doi.org/10.3389/fbioe.2014.00032
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AT nielsenjens fattyacidderivedbiofuelsandchemicalsproductioninsaccharomycescerevisiae