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Lithium Regulates Keratinocyte Proliferation Via Glycogen Synthase Kinase 3 and NFAT2 (Nuclear Factor of Activated T Cells 2)

Certain environmental factors including drugs exacerbate or precipitate psoriasis. Lithium is the commonest cause of drug-induced psoriasis but underlying mechanisms are currently unknown. Lithium inhibits glycogen synthase kinase 3 (GSK-3). As lithium does not exacerbate other T-cell-mediated chron...

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Detalles Bibliográficos
Autores principales: Hampton, Philip J, Jans, Ralph, Flockhart, Ross J, Parker, Graeme, Reynolds, Nick J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150531/
https://www.ncbi.nlm.nih.gov/pubmed/21678407
http://dx.doi.org/10.1002/jcp.22872