Hippocampal seizure-onset laterality can change over long timescales: A same-patient observation over 500 days()

This study describes seizure laterality and localization changes over 500 consecutive days in a patient with bilateral temporal lobe epilepsy (BTLE) and implanted NeuroPace RNS™ System. During a continuous two-year time period, the RNS™ device stored 54 hippocampal electrocorticography (ECoG) seizur...

Descripción completa

Detalles Bibliográficos
Autores principales: Smart, Otis, Rolston, John D., Epstein, Charles M., Gross, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150592/
https://www.ncbi.nlm.nih.gov/pubmed/25667828
http://dx.doi.org/10.1016/j.ebcr.2013.03.003
_version_ 1782332929292107776
author Smart, Otis
Rolston, John D.
Epstein, Charles M.
Gross, Robert E.
author_facet Smart, Otis
Rolston, John D.
Epstein, Charles M.
Gross, Robert E.
author_sort Smart, Otis
collection PubMed
description This study describes seizure laterality and localization changes over 500 consecutive days in a patient with bilateral temporal lobe epilepsy (BTLE) and implanted NeuroPace RNS™ System. During a continuous two-year time period, the RNS™ device stored 54 hippocampal electrocorticography (ECoG) seizures, which we analyzed to determine their distribution and time variance across hippocampi. We report nonrandom long-term seizure laterality and localization variations, especially in the first 200 days postimplant, despite equivalent total seizure counts in both hippocampi. This case suggests that hippocampal seizures dynamically progress over extensive timescales.
format Online
Article
Text
id pubmed-4150592
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-41505922015-02-09 Hippocampal seizure-onset laterality can change over long timescales: A same-patient observation over 500 days() Smart, Otis Rolston, John D. Epstein, Charles M. Gross, Robert E. Epilepsy Behav Case Rep Case Report This study describes seizure laterality and localization changes over 500 consecutive days in a patient with bilateral temporal lobe epilepsy (BTLE) and implanted NeuroPace RNS™ System. During a continuous two-year time period, the RNS™ device stored 54 hippocampal electrocorticography (ECoG) seizures, which we analyzed to determine their distribution and time variance across hippocampi. We report nonrandom long-term seizure laterality and localization variations, especially in the first 200 days postimplant, despite equivalent total seizure counts in both hippocampi. This case suggests that hippocampal seizures dynamically progress over extensive timescales. Elsevier 2013-04-13 /pmc/articles/PMC4150592/ /pubmed/25667828 http://dx.doi.org/10.1016/j.ebcr.2013.03.003 Text en © 2013 The Authors http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open access article under the CC BY-NC-SA license (http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Case Report
Smart, Otis
Rolston, John D.
Epstein, Charles M.
Gross, Robert E.
Hippocampal seizure-onset laterality can change over long timescales: A same-patient observation over 500 days()
title Hippocampal seizure-onset laterality can change over long timescales: A same-patient observation over 500 days()
title_full Hippocampal seizure-onset laterality can change over long timescales: A same-patient observation over 500 days()
title_fullStr Hippocampal seizure-onset laterality can change over long timescales: A same-patient observation over 500 days()
title_full_unstemmed Hippocampal seizure-onset laterality can change over long timescales: A same-patient observation over 500 days()
title_short Hippocampal seizure-onset laterality can change over long timescales: A same-patient observation over 500 days()
title_sort hippocampal seizure-onset laterality can change over long timescales: a same-patient observation over 500 days()
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150592/
https://www.ncbi.nlm.nih.gov/pubmed/25667828
http://dx.doi.org/10.1016/j.ebcr.2013.03.003
work_keys_str_mv AT smartotis hippocampalseizureonsetlateralitycanchangeoverlongtimescalesasamepatientobservationover500days
AT rolstonjohnd hippocampalseizureonsetlateralitycanchangeoverlongtimescalesasamepatientobservationover500days
AT epsteincharlesm hippocampalseizureonsetlateralitycanchangeoverlongtimescalesasamepatientobservationover500days
AT grossroberte hippocampalseizureonsetlateralitycanchangeoverlongtimescalesasamepatientobservationover500days

Ejemplares similares