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Epilepsy surgery of dysembryoplastic neuroepithelial tumors using advanced multitechnologies with combined neuroimaging and electrophysiological examinations()

PURPOSE: We report three cases of dysembryoplastic neuroepithelial tumor (DNT) with intractable epilepsy which were successfully treated with surgery. METHODS: In all cases, technology beyond the routine workup was critical to success. Preoperative magnetic resonance imaging, (18)F-fluorodeoxyglucos...

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Autores principales: Shinoda, Jun, Yokoyama, Kazutoshi, Miwa, Kazuhiro, Ito, Takeshi, Asano, Yoshitaka, Yonezawa, Shingo, Yano, Hirohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150595/
https://www.ncbi.nlm.nih.gov/pubmed/25667839
http://dx.doi.org/10.1016/j.ebcr.2013.06.002
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author Shinoda, Jun
Yokoyama, Kazutoshi
Miwa, Kazuhiro
Ito, Takeshi
Asano, Yoshitaka
Yonezawa, Shingo
Yano, Hirohito
author_facet Shinoda, Jun
Yokoyama, Kazutoshi
Miwa, Kazuhiro
Ito, Takeshi
Asano, Yoshitaka
Yonezawa, Shingo
Yano, Hirohito
author_sort Shinoda, Jun
collection PubMed
description PURPOSE: We report three cases of dysembryoplastic neuroepithelial tumor (DNT) with intractable epilepsy which were successfully treated with surgery. METHODS: In all cases, technology beyond the routine workup was critical to success. Preoperative magnetic resonance imaging, (18)F-fluorodeoxyglucose positron emission tomography (PET), (11)C-methionine-PET, interictal electroencephalography, and intraoperative electrocorticography were utilized in all patients. In individual cases, however, additional procedures such as preoperative magnetoencephalography (Case 1), diffusion tensor fiber tractography, a neuronavigation system, and intraoperative somatosensory-evoked potential (Case 2), and fiber tractography and the neuronavigation-guided fence-post tube technique (Case 3) were instrumental. RESULTS: In all the cases, the objectives of total tumor resection, resection of the epileptogenic zone, and complete postoperative seizure control and the avoidance of surgical complications were achieved. CONCLUSIONS: Dysembryoplastic neuroepithelial tumor is commonly associated with medically intractable epilepsy, and surgery is frequently utilized. As DNT may arise in any supratentorial and intracortical locations within or near the critical area of the brain, meticulous surgical strategies are necessary to avoid neurological deficits. We demonstrate in the following three cases how adjunct procedures using advanced multitechnologies with neuroimaging and electrophysiological examinations may be utilized to ensure success in DNT surgery.
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spelling pubmed-41505952015-02-09 Epilepsy surgery of dysembryoplastic neuroepithelial tumors using advanced multitechnologies with combined neuroimaging and electrophysiological examinations() Shinoda, Jun Yokoyama, Kazutoshi Miwa, Kazuhiro Ito, Takeshi Asano, Yoshitaka Yonezawa, Shingo Yano, Hirohito Epilepsy Behav Case Rep Case Report PURPOSE: We report three cases of dysembryoplastic neuroepithelial tumor (DNT) with intractable epilepsy which were successfully treated with surgery. METHODS: In all cases, technology beyond the routine workup was critical to success. Preoperative magnetic resonance imaging, (18)F-fluorodeoxyglucose positron emission tomography (PET), (11)C-methionine-PET, interictal electroencephalography, and intraoperative electrocorticography were utilized in all patients. In individual cases, however, additional procedures such as preoperative magnetoencephalography (Case 1), diffusion tensor fiber tractography, a neuronavigation system, and intraoperative somatosensory-evoked potential (Case 2), and fiber tractography and the neuronavigation-guided fence-post tube technique (Case 3) were instrumental. RESULTS: In all the cases, the objectives of total tumor resection, resection of the epileptogenic zone, and complete postoperative seizure control and the avoidance of surgical complications were achieved. CONCLUSIONS: Dysembryoplastic neuroepithelial tumor is commonly associated with medically intractable epilepsy, and surgery is frequently utilized. As DNT may arise in any supratentorial and intracortical locations within or near the critical area of the brain, meticulous surgical strategies are necessary to avoid neurological deficits. We demonstrate in the following three cases how adjunct procedures using advanced multitechnologies with neuroimaging and electrophysiological examinations may be utilized to ensure success in DNT surgery. Elsevier 2013-07-27 /pmc/articles/PMC4150595/ /pubmed/25667839 http://dx.doi.org/10.1016/j.ebcr.2013.06.002 Text en © 2013 The Authors https://creativecommons.org/licenses/by/3.0/This work is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/) .
spellingShingle Case Report
Shinoda, Jun
Yokoyama, Kazutoshi
Miwa, Kazuhiro
Ito, Takeshi
Asano, Yoshitaka
Yonezawa, Shingo
Yano, Hirohito
Epilepsy surgery of dysembryoplastic neuroepithelial tumors using advanced multitechnologies with combined neuroimaging and electrophysiological examinations()
title Epilepsy surgery of dysembryoplastic neuroepithelial tumors using advanced multitechnologies with combined neuroimaging and electrophysiological examinations()
title_full Epilepsy surgery of dysembryoplastic neuroepithelial tumors using advanced multitechnologies with combined neuroimaging and electrophysiological examinations()
title_fullStr Epilepsy surgery of dysembryoplastic neuroepithelial tumors using advanced multitechnologies with combined neuroimaging and electrophysiological examinations()
title_full_unstemmed Epilepsy surgery of dysembryoplastic neuroepithelial tumors using advanced multitechnologies with combined neuroimaging and electrophysiological examinations()
title_short Epilepsy surgery of dysembryoplastic neuroepithelial tumors using advanced multitechnologies with combined neuroimaging and electrophysiological examinations()
title_sort epilepsy surgery of dysembryoplastic neuroepithelial tumors using advanced multitechnologies with combined neuroimaging and electrophysiological examinations()
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150595/
https://www.ncbi.nlm.nih.gov/pubmed/25667839
http://dx.doi.org/10.1016/j.ebcr.2013.06.002
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