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Surgical treatment of refractory epilepsy after chemotherapy in two children with leukemia()
Refractory epilepsy is a rare, long-term complication in children with acute leukemia who are receiving chemotherapy. A few studies have reported cases of several patients who developed recurrent complex partial seizures after the initiation of chemotherapy. In these cases, the cause of the refracto...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150597/ https://www.ncbi.nlm.nih.gov/pubmed/25667821 http://dx.doi.org/10.1016/j.ebcr.2012.12.001 |
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author | Leng, Yun Yu, Tao Li, Yongjie Chen, Wenming |
author_facet | Leng, Yun Yu, Tao Li, Yongjie Chen, Wenming |
author_sort | Leng, Yun |
collection | PubMed |
description | Refractory epilepsy is a rare, long-term complication in children with acute leukemia who are receiving chemotherapy. A few studies have reported cases of several patients who developed recurrent complex partial seizures after the initiation of chemotherapy. In these cases, the cause of the refractory seizures was identified as mesial temporal lobe sclerosis. Here, we report on two patients with extratemporal lesions accompanied by refractory seizures, a long-term complication of acute lymphocytic leukemia. Using presurgical evaluations and measures of the surgical outcomes, the lesions were identified as epileptogenic and were located in the mesial temporal lobe. The underlying pathophysiological background is discussed to aid in understanding this uncommon long-term complication. |
format | Online Article Text |
id | pubmed-4150597 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-41505972015-02-09 Surgical treatment of refractory epilepsy after chemotherapy in two children with leukemia() Leng, Yun Yu, Tao Li, Yongjie Chen, Wenming Epilepsy Behav Case Rep Case Report Refractory epilepsy is a rare, long-term complication in children with acute leukemia who are receiving chemotherapy. A few studies have reported cases of several patients who developed recurrent complex partial seizures after the initiation of chemotherapy. In these cases, the cause of the refractory seizures was identified as mesial temporal lobe sclerosis. Here, we report on two patients with extratemporal lesions accompanied by refractory seizures, a long-term complication of acute lymphocytic leukemia. Using presurgical evaluations and measures of the surgical outcomes, the lesions were identified as epileptogenic and were located in the mesial temporal lobe. The underlying pathophysiological background is discussed to aid in understanding this uncommon long-term complication. Elsevier 2013-02-04 /pmc/articles/PMC4150597/ /pubmed/25667821 http://dx.doi.org/10.1016/j.ebcr.2012.12.001 Text en © 2013 The Authors https://creativecommons.org/licenses/by/3.0/This work is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/) . |
spellingShingle | Case Report Leng, Yun Yu, Tao Li, Yongjie Chen, Wenming Surgical treatment of refractory epilepsy after chemotherapy in two children with leukemia() |
title | Surgical treatment of refractory epilepsy after chemotherapy in two children with leukemia() |
title_full | Surgical treatment of refractory epilepsy after chemotherapy in two children with leukemia() |
title_fullStr | Surgical treatment of refractory epilepsy after chemotherapy in two children with leukemia() |
title_full_unstemmed | Surgical treatment of refractory epilepsy after chemotherapy in two children with leukemia() |
title_short | Surgical treatment of refractory epilepsy after chemotherapy in two children with leukemia() |
title_sort | surgical treatment of refractory epilepsy after chemotherapy in two children with leukemia() |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150597/ https://www.ncbi.nlm.nih.gov/pubmed/25667821 http://dx.doi.org/10.1016/j.ebcr.2012.12.001 |
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