Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies()

Hashimoto's encephalopathy is defined by the coexistence of encephalopathy and antithyroid antibodies. We report two cases of adult-onset temporal lobe epilepsy with subacute cognitive decline, high titers of antithyroid antibodies, multi-antiepileptic drug hypersensitivity, and good response t...

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Detalles Bibliográficos
Autores principales: Sadan, Ofer, Seyman, Estelle, Ash, Elissa L., Kipervasser, Svetlana, Neufeld, Miri Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150645/
https://www.ncbi.nlm.nih.gov/pubmed/25667846
http://dx.doi.org/10.1016/j.ebcr.2013.07.004
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author Sadan, Ofer
Seyman, Estelle
Ash, Elissa L.
Kipervasser, Svetlana
Neufeld, Miri Y.
author_facet Sadan, Ofer
Seyman, Estelle
Ash, Elissa L.
Kipervasser, Svetlana
Neufeld, Miri Y.
author_sort Sadan, Ofer
collection PubMed
description Hashimoto's encephalopathy is defined by the coexistence of encephalopathy and antithyroid antibodies. We report two cases of adult-onset temporal lobe epilepsy with subacute cognitive decline, high titers of antithyroid antibodies, multi-antiepileptic drug hypersensitivity, and good response to immunomodulatory treatment. The relevance of multidrug hypersensitivity in the setting of adult-onset epilepsy and the importance of searching for autoimmune causes for epilepsy are discussed.
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spelling pubmed-41506452015-02-09 Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies() Sadan, Ofer Seyman, Estelle Ash, Elissa L. Kipervasser, Svetlana Neufeld, Miri Y. Epilepsy Behav Case Rep Case Report Hashimoto's encephalopathy is defined by the coexistence of encephalopathy and antithyroid antibodies. We report two cases of adult-onset temporal lobe epilepsy with subacute cognitive decline, high titers of antithyroid antibodies, multi-antiepileptic drug hypersensitivity, and good response to immunomodulatory treatment. The relevance of multidrug hypersensitivity in the setting of adult-onset epilepsy and the importance of searching for autoimmune causes for epilepsy are discussed. Elsevier 2013-08-31 /pmc/articles/PMC4150645/ /pubmed/25667846 http://dx.doi.org/10.1016/j.ebcr.2013.07.004 Text en © 2013 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Case Report
Sadan, Ofer
Seyman, Estelle
Ash, Elissa L.
Kipervasser, Svetlana
Neufeld, Miri Y.
Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies()
title Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies()
title_full Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies()
title_fullStr Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies()
title_full_unstemmed Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies()
title_short Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies()
title_sort adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and hashimoto's encephalopathy: two case studies()
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150645/
https://www.ncbi.nlm.nih.gov/pubmed/25667846
http://dx.doi.org/10.1016/j.ebcr.2013.07.004
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