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A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies

Dysregulation of the insulin-like growth factor type I receptor (IGF1R) has been implicated in the progression and therapeutic resistance of malignancies. In acute myeloid leukemia (AML) cells, IGF1R is one of the most abundantly phosphorylated receptor tyrosine kinases, promoting cell growth throug...

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Detalles Bibliográficos
Autores principales:	Sun, Jingnan, Li, Wei, Sun, Yunpeng, Yu, Dehai, Wen, Xue, Wang, Hong, Cui, Jiuwei, Wang, Guanjun, Hoffman, Andrew R., Hu, Ji-Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150754/ https://www.ncbi.nlm.nih.gov/pubmed/25092925 http://dx.doi.org/10.1093/nar/gku549

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