Architectural proteins CTCF and cohesin have distinct roles in modulating the higher order structure and expression of the CFTR locus

Higher order chromatin structures across the genome are maintained in part by the architectural proteins CCCTC binding factor (CTCF) and the cohesin complex, which co-localize at many sites across the genome. Here, we examine the role of these proteins in mediating chromatin structure at the cystic...

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Detalles Bibliográficos
Autores principales: Gosalia, Nehal, Neems, Daniel, Kerschner, Jenny L., Kosak, Steven T., Harris, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150766/
https://www.ncbi.nlm.nih.gov/pubmed/25081205
http://dx.doi.org/10.1093/nar/gku648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150766/
https://www.ncbi.nlm.nih.gov/pubmed/25081205
http://dx.doi.org/10.1093/nar/gku648

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