ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK–RSK pathway

Low-density lipoprotein receptor (LDLR) mRNA is unstable, but is stabilized upon extracellular signal-regulated kinase (ERK) activation, possibly through the binding of certain proteins to the LDLR mRNA 3′-untranslated region (UTR), although the detailed mechanism underlying this stability control i...

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Detalles Bibliográficos
Autores principales: Adachi, Shungo, Homoto, Masae, Tanaka, Rikou, Hioki, Yusaku, Murakami, Hiroshi, Suga, Hiroaki, Matsumoto, Masaki, Nakayama, Keiichi I., Hatta, Tomohisa, Iemura, Shun-ichiro, Natsume, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150769/
https://www.ncbi.nlm.nih.gov/pubmed/25106868
http://dx.doi.org/10.1093/nar/gku652

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