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The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence

Nearly all bacteria exhibit a type of phenotypic growth described as persistence that is thought to underlie antibiotic tolerance and recalcitrant chronic infections. The chromosomally encoded high-persistence (Hip) toxin–antitoxin proteins HipA(SO) and HipB(SO) from Shewanella oneidensis, a proteob...

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Detalles Bibliográficos
Autores principales:	Wen, Yurong, Behiels, Ester, Felix, Jan, Elegheert, Jonathan, Vergauwen, Bjorn, Devreese, Bart, Savvides, Savvas N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150777/ https://www.ncbi.nlm.nih.gov/pubmed/25056321 http://dx.doi.org/10.1093/nar/gku665

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