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Engineering the elongation factor Tu for efficient selenoprotein synthesis

Selenocysteine (Sec) is naturally co-translationally incorporated into proteins by recoding the UGA opal codon with a specialized elongation factor (SelB in bacteria) and an RNA structural signal (SECIS element). We have recently developed a SECIS-free selenoprotein synthesis system that site-specif...

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Detalles Bibliográficos
Autores principales:	Haruna, Ken-ichi, Alkazemi, Muhammad H., Liu, Yuchen, Söll, Dieter, Englert, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150793/ https://www.ncbi.nlm.nih.gov/pubmed/25064855 http://dx.doi.org/10.1093/nar/gku691

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