ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1

Epithelial-mesenchymal transition (EMT) is associated with characteristics of breast cancer stem cells, including chemoresistance and radioresistance. However, it is unclear whether EMT itself or specific EMT regulators play causal roles in these properties. Here we identify an EMT-inducing transcri...

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Detalles Bibliográficos
Autores principales: Zhang, Peijing, Wei, Yongkun, Wang, Li, Debeb, Bisrat G., Yuan, Yuan, Zhang, Jinsong, Yuan, Jingsong, Wang, Min, Chen, Dahu, Sun, Yutong, Woodward, Wendy A., Liu, Yongqing, Dean, Douglas C., Liang, Han, Hu, Ye, Ang, K. Kian, Hung, Mien-Chie, Chen, Junjie, Ma, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150825/
https://www.ncbi.nlm.nih.gov/pubmed/25086746
http://dx.doi.org/10.1038/ncb3013

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