Cargando…

Oncogenic RIT1 mutations in lung adenocarcinoma

Lung adenocarcinoma is comprised of distinct mutational subtypes characterized by mutually exclusive oncogenic mutations in RTK/RAS pathway members KRAS, EGFR, BRAF and ERBB2, and translocations involving ALK, RET and ROS1. Identification of these oncogenic events has transformed the treatment of lu...

Descripción completa

Detalles Bibliográficos
Autores principales: Berger, A H, Imielinski, M, Duke, F, Wala, J, Kaplan, N, Shi, G-X, Andres, D A, Meyerson, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150988/
https://www.ncbi.nlm.nih.gov/pubmed/24469055
http://dx.doi.org/10.1038/onc.2013.581