Anticancer Drug 2-Methoxyestradiol Protects against Renal Ischemia/Reperfusion Injury by Reducing Inflammatory Cytokines Expression

Background. Ischemia/reperfusion (I/R) injury is a major cause of acute renal failure and allograft dysfunction in kidney transplantation. ROS/inflammatory cytokines are involved in I/R injury. 2-Methoxyestradiol (2ME2), an endogenous metabolite of estradiol, inhibits inflammatory cytokine expressio...

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Detalles Bibliográficos
Autores principales: Chen, Ying-Yin, Yeh, Ching-Hua, So, Edmund Cheung, Sun, Ding-Ping, Wang, Li-Yun, Hsing, Chung-Hsi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151070/
https://www.ncbi.nlm.nih.gov/pubmed/25229058
http://dx.doi.org/10.1155/2014/431524

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