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Microtubules provide directional information for core PCP function

Planar cell polarity (PCP) signaling controls the polarization of cells within the plane of an epithelium. Two molecular modules composed of Fat(Ft)/Dachsous(Ds)/Four-jointed(Fj) and a ‘PCP-core’ including Frizzled(Fz) and Dishevelled(Dsh) contribute to polarization of individual cells. How polarity...

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Detalles Bibliográficos
Autores principales:	Matis, Maja, Russler-Germain, David A, Hu, Qie, Tomlin, Claire J, Axelrod, Jeffrey D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151085/ https://www.ncbi.nlm.nih.gov/pubmed/25124458 http://dx.doi.org/10.7554/eLife.02893

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