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Sphingomyelin homeostasis is required to form functional enzymatic domains at the trans-Golgi network

Do lipids such as sphingomyelin (SM) that are known to assemble into specific membrane domains play a role in the organization and function of transmembrane proteins? In this paper, we show that disruption of SM homeostasis at the trans-Golgi network (TGN) by treatment of HeLa cells with d-ceramide-...

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Detalles Bibliográficos
Autores principales:	van Galen, Josse, Campelo, Felix, Martínez-Alonso, Emma, Scarpa, Margherita, Martínez-Menárguez, José Ángel, Malhotra, Vivek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151138/ https://www.ncbi.nlm.nih.gov/pubmed/25179630 http://dx.doi.org/10.1083/jcb.201405009

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