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UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity
The receptor deleted in colorectal cancer (DCC) directs dynamic polarizing activities in animals toward its extracellular ligand netrin. How DCC polarizes toward netrin is poorly understood. By performing live-cell imaging of the DCC orthologue UNC-40 during anchor cell invasion in Caenorhabditis el...
Autores principales: | Wang, Zheng, Linden, Lara M., Naegeli, Kaleb M., Ziel, Joshua W., Chi, Qiuyi, Hagedorn, Elliott J., Savage, Natasha S., Sherwood, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151141/ https://www.ncbi.nlm.nih.gov/pubmed/25154398 http://dx.doi.org/10.1083/jcb.201405026 |
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