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Cofilin recruits F-actin to SPCA1 and promotes Ca(2+)-mediated secretory cargo sorting
The actin filament severing protein cofilin-1 (CFL-1) is required for actin and P-type ATPase secretory pathway calcium ATPase (SPCA)-dependent sorting of secretory proteins at the trans-Golgi network (TGN). How these proteins interact and activate the pump to facilitate cargo sorting, however, is n...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151145/ https://www.ncbi.nlm.nih.gov/pubmed/25179631 http://dx.doi.org/10.1083/jcb.201311052 |