Murine lung injury caused by Leptospira interrogans glycolipoprotein, a specific Na/K-ATPase inhibitor

BACKGROUND: Leptospiral glycolipoprotein (GLP) is a potent and specific Na/K-ATPase inhibitor. Severe pulmonary form of leptospirosis is characterized by edema, inflammation and intra-alveolar hemorrhage having a dismal prognosis. Resolution of edema and inflammation determines the outcome of lung i...

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Detalles Bibliográficos
Autores principales: Gonçalves-de-Albuquerque, Cassiano Felippe, Burth, Patrícia, Silva, Adriana Ribeiro, de Moraes, Isabel Matos Medeiros, Oliveira, Flora Magno de Jesus, Santelli, Ricardo Erthal, Freire, Aline Soares, de Lima, Gerson Silva, da Silva, Emilson Domingos, da Silva, Camila Ignácio, Morandi, Verônica, Bozza, Patrícia Torres, Younes-Ibrahim, Mauricio, de Castro Faria Neto, Hugo Caire, de Castro Faria, Mauro Velho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151191/
https://www.ncbi.nlm.nih.gov/pubmed/25265888
http://dx.doi.org/10.1186/s12931-014-0093-2

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