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Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondria
Lysine modifications have been studied extensively in the nucleus, where they play pivotal roles in gene regulation and constitute one of the pillars of epigenetics. In the cytoplasm, they are critical to proteostasis. However, in the last decade we have also witnessed the emergence of mitochondria...
Autores principales: | Papanicolaou, Kyriakos N., O'Rourke, Brian, Foster, D. Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151196/ https://www.ncbi.nlm.nih.gov/pubmed/25228883 http://dx.doi.org/10.3389/fphys.2014.00301 |
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