Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity

Cells differentiate when transcription factors (TFs) bind accessible cis-regulatory elements to establish specific gene expression programs. In differentiating embryonic stem (ES) cells, chromatin at lineage-restricted genes becomes sequentially accessible(1-4), probably by virtue of “pioneer” TF ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Tae-Hee, Li, Fugen, Ferreiro-Neira, Isabel, Ho, Li-Lun, Luyten, Annouck, Nalapareddy, Kodandaramireddy, Long, Henry, Verzi, Michael, Shivdasani, Ramesh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151315/
https://www.ncbi.nlm.nih.gov/pubmed/24413398
http://dx.doi.org/10.1038/nature12903

Ejemplares similares

Ejemplares similares