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Converting a Binding Protein into a Biosensing Conformational Switch Using Protein Fragment Exchange
[Image: see text] Biosensors can be used in applications ranging from identifying disease biomarkers to detecting spatial and temporal distributions of specific molecules in living cells. A major challenge facing biosensor development is how to functionally couple a biological recognition domain to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151334/ https://www.ncbi.nlm.nih.gov/pubmed/25084233 http://dx.doi.org/10.1021/bi500758u |