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Identification of Cleavage Sites Leading to the Shed Form of the Anti-Aging Protein Klotho

[Image: see text] Membrane protein shedding is a critical step in many normal and pathological processes. The anti-aging protein klotho (KL), mainly expressed in kidney and brain, is secreted into the serum and CSF, respectively. KL is proteolytically released, or shed, from the cell surface by ADAM...

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Detalles Bibliográficos
Autores principales:	Chen, Ci-Di, Tung, Tze Yu, Liang, Jennifer, Zeldich, Ella, Tucker Zhou, Tracey B., Turk, Benjamin E., Abraham, Carmela R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151695/ https://www.ncbi.nlm.nih.gov/pubmed/25110992 http://dx.doi.org/10.1021/bi500409n

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