A novel system for predicting the toxicity of irinotecan based on statistical pattern recognition with UGT1A genotypes

To predict precisely severe toxicity of irinotecan, we evaluated the association of UGT1A variants, haplotypes and the combination of UGT1A genotypes to severe toxicity of irinotecan. UGT1A1*6 (211G>A), UGT1A1*28 (TA(6)>TA(7)), UGT1A1*60 (−3279T>G), UGT1A7 (387T>G), UGT1A7 (622T>C), a...

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Detalles Bibliográficos
Autores principales: TSUNEDOMI, RYOUICHI, HAZAMA, SHOICHI, FUJITA, YUSUKE, OKAYAMA, NAOKO, KANEKIYO, SHINSUKE, INOUE, YUKA, YOSHINO, SHIGEFUMI, YAMASAKI, TAKAHIRO, SUEHIRO, YUTA KA, OBA, KOJI, MISHIMA, HIDEYUKI, SAKAMOTO, JUNICHI, HAMAMOTO, YOSHIHIKO, OKA, MASAKI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151810/
https://www.ncbi.nlm.nih.gov/pubmed/25175642
http://dx.doi.org/10.3892/ijo.2014.2556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151810/
https://www.ncbi.nlm.nih.gov/pubmed/25175642
http://dx.doi.org/10.3892/ijo.2014.2556

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