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Variations in metabolic pathways create challenges for automated metabolic reconstructions: Examples from the tetrahydrofolate synthesis pathway
The availability of thousands of sequenced genomes has revealed the diversity of biochemical solutions to similar chemical problems. Even for molecules at the heart of metabolism, such as cofactors, the pathway enzymes first discovered in model organisms like Escherichia coli or Saccharomyces cerevi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Research Network of Computational and Structural Biotechnology
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151868/ https://www.ncbi.nlm.nih.gov/pubmed/25210598 http://dx.doi.org/10.1016/j.csbj.2014.05.008 |