Cargando…

Prevalence of Metabolic Syndrome: Association with Risk Factors and Cardiovascular Complications in an Urban Population

INTRODUCTION: Metabolic syndrome (MS) is a set of cardiovascular risk factors and type 2 diabetes, responsible for a 2.5-fold increased cardiovascular mortality and a 5-fold higher risk of developing diabetes. OBJECTIVES: 1-to evaluate the prevalence of MS in individuals over 18 years associated wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Moreira, Gisela Cipullo, Cipullo, José Paulo, Ciorlia, Luiz Alberto Souza, Cesarino, Cláudia Bernardi, Vilela-Martin, José Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152120/
https://www.ncbi.nlm.nih.gov/pubmed/25180496
http://dx.doi.org/10.1371/journal.pone.0105056
_version_ 1782333081042026496
author Moreira, Gisela Cipullo
Cipullo, José Paulo
Ciorlia, Luiz Alberto Souza
Cesarino, Cláudia Bernardi
Vilela-Martin, José Fernando
author_facet Moreira, Gisela Cipullo
Cipullo, José Paulo
Ciorlia, Luiz Alberto Souza
Cesarino, Cláudia Bernardi
Vilela-Martin, José Fernando
author_sort Moreira, Gisela Cipullo
collection PubMed
description INTRODUCTION: Metabolic syndrome (MS) is a set of cardiovascular risk factors and type 2 diabetes, responsible for a 2.5-fold increased cardiovascular mortality and a 5-fold higher risk of developing diabetes. OBJECTIVES: 1-to evaluate the prevalence of MS in individuals over 18 years associated with age, gender, socioeconomic status, educational levels, body mass index (BMI), HOMA index and physical activity; moreover, to compare it to other studies; 2-to compare the prevalence of elevated blood pressure (BP), high triglycerides and plasma glucose levels, low HDL cholesterol and high waist circumference among individuals with MS also according to gender; 3-to determine the number of risk factors in subjects with MS and prevalence of complications in individuals with and without MS aged over 40 years. METHODS: A cross-sectional study of 1369 Individuals, 667 males (48.7%) and 702 females (51.3%) was considered to evaluate the prevalence of MS and associated factors in the population. RESULTS: The study showed that 22.7% (95% CI: 19.4% to 26.0%) of the population has MS, which increases with age, higher BMI and sedentary lifestyle. There was no significant difference between genders until age ≥70 years and social classes. Higher prevalence of MS was observed in lower educational levels and higher prevalence of HOMA positive among individuals with MS. The most prevalent risk factors were elevated blood pressure (85%), low HDL cholesterol (83.1%) and increased waist circumference (82.5%). The prevalence of elevated BP, low HDL cholesterol and plasma glucose levels did not show significant difference between genders. Individuals with MS had higher risk of cardiovascular complications over 40 years. CONCLUSION: The prevalence of MS found is similar to that in developed countries, being influenced by age, body mass index, educational levels, physical activity, and leading to a higher prevalence of cardiovascular complications after the 4th decade of life.
format Online
Article
Text
id pubmed-4152120
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-41521202014-09-05 Prevalence of Metabolic Syndrome: Association with Risk Factors and Cardiovascular Complications in an Urban Population Moreira, Gisela Cipullo Cipullo, José Paulo Ciorlia, Luiz Alberto Souza Cesarino, Cláudia Bernardi Vilela-Martin, José Fernando PLoS One Research Article INTRODUCTION: Metabolic syndrome (MS) is a set of cardiovascular risk factors and type 2 diabetes, responsible for a 2.5-fold increased cardiovascular mortality and a 5-fold higher risk of developing diabetes. OBJECTIVES: 1-to evaluate the prevalence of MS in individuals over 18 years associated with age, gender, socioeconomic status, educational levels, body mass index (BMI), HOMA index and physical activity; moreover, to compare it to other studies; 2-to compare the prevalence of elevated blood pressure (BP), high triglycerides and plasma glucose levels, low HDL cholesterol and high waist circumference among individuals with MS also according to gender; 3-to determine the number of risk factors in subjects with MS and prevalence of complications in individuals with and without MS aged over 40 years. METHODS: A cross-sectional study of 1369 Individuals, 667 males (48.7%) and 702 females (51.3%) was considered to evaluate the prevalence of MS and associated factors in the population. RESULTS: The study showed that 22.7% (95% CI: 19.4% to 26.0%) of the population has MS, which increases with age, higher BMI and sedentary lifestyle. There was no significant difference between genders until age ≥70 years and social classes. Higher prevalence of MS was observed in lower educational levels and higher prevalence of HOMA positive among individuals with MS. The most prevalent risk factors were elevated blood pressure (85%), low HDL cholesterol (83.1%) and increased waist circumference (82.5%). The prevalence of elevated BP, low HDL cholesterol and plasma glucose levels did not show significant difference between genders. Individuals with MS had higher risk of cardiovascular complications over 40 years. CONCLUSION: The prevalence of MS found is similar to that in developed countries, being influenced by age, body mass index, educational levels, physical activity, and leading to a higher prevalence of cardiovascular complications after the 4th decade of life. Public Library of Science 2014-09-02 /pmc/articles/PMC4152120/ /pubmed/25180496 http://dx.doi.org/10.1371/journal.pone.0105056 Text en © 2014 Moreira et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Moreira, Gisela Cipullo
Cipullo, José Paulo
Ciorlia, Luiz Alberto Souza
Cesarino, Cláudia Bernardi
Vilela-Martin, José Fernando
Prevalence of Metabolic Syndrome: Association with Risk Factors and Cardiovascular Complications in an Urban Population
title Prevalence of Metabolic Syndrome: Association with Risk Factors and Cardiovascular Complications in an Urban Population
title_full Prevalence of Metabolic Syndrome: Association with Risk Factors and Cardiovascular Complications in an Urban Population
title_fullStr Prevalence of Metabolic Syndrome: Association with Risk Factors and Cardiovascular Complications in an Urban Population
title_full_unstemmed Prevalence of Metabolic Syndrome: Association with Risk Factors and Cardiovascular Complications in an Urban Population
title_short Prevalence of Metabolic Syndrome: Association with Risk Factors and Cardiovascular Complications in an Urban Population
title_sort prevalence of metabolic syndrome: association with risk factors and cardiovascular complications in an urban population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152120/
https://www.ncbi.nlm.nih.gov/pubmed/25180496
http://dx.doi.org/10.1371/journal.pone.0105056
work_keys_str_mv AT moreiragiselacipullo prevalenceofmetabolicsyndromeassociationwithriskfactorsandcardiovascularcomplicationsinanurbanpopulation
AT cipullojosepaulo prevalenceofmetabolicsyndromeassociationwithriskfactorsandcardiovascularcomplicationsinanurbanpopulation
AT ciorlialuizalbertosouza prevalenceofmetabolicsyndromeassociationwithriskfactorsandcardiovascularcomplicationsinanurbanpopulation
AT cesarinoclaudiabernardi prevalenceofmetabolicsyndromeassociationwithriskfactorsandcardiovascularcomplicationsinanurbanpopulation
AT vilelamartinjosefernando prevalenceofmetabolicsyndromeassociationwithriskfactorsandcardiovascularcomplicationsinanurbanpopulation