Differential Binding of Tenofovir and Adefovir to Reverse Transcriptase of Hepatitis B Virus

INTRODUCTION: Resistance of the reverse transcriptase (RT) of hepatitis B virus (HBV) to the tenofovir nucleotide drug has not been observed since its introduction for treatment of hepatitis B virus (HBV) infection in 2008. In contrast, frequent viral breakthrough and resistance has been documented...

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Detalles Bibliográficos
Autores principales: van Hemert, Formijn J., Berkhout, Ben, Zaaijer, Hans L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152281/
https://www.ncbi.nlm.nih.gov/pubmed/25180507
http://dx.doi.org/10.1371/journal.pone.0106324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152281/
https://www.ncbi.nlm.nih.gov/pubmed/25180507
http://dx.doi.org/10.1371/journal.pone.0106324

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