Comparison of the Anti-Prion Mechanism of Four Different Anti-Prion Compounds, Anti-PrP Monoclonal Antibody 44B1, Pentosan Polysulfate, Chlorpromazine, and U18666A, in Prion-Infected Mouse Neuroblastoma Cells

Molecules that inhibit the formation of an abnormal isoform of prion protein (PrP(Sc)) in prion-infected cells are candidate therapeutic agents for prion diseases. Understanding how these molecules inhibit PrP(Sc) formation provides logical basis for proper evaluation of their therapeutic potential....

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Detalles Bibliográficos
Autores principales: Yamasaki, Takeshi, Suzuki, Akio, Hasebe, Rie, Horiuchi, Motohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152300/
https://www.ncbi.nlm.nih.gov/pubmed/25181483
http://dx.doi.org/10.1371/journal.pone.0106516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152300/
https://www.ncbi.nlm.nih.gov/pubmed/25181483
http://dx.doi.org/10.1371/journal.pone.0106516

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