Elevated levels of exhaled nitric oxide in patients with anorexia nervosa

BACKGROUND: Nitric oxide (NO) is involved in eating behavior and inflammatory response. Moreover, there is evidence that NO production is altered in patients with anorexia nervosa (AN). AIM: To assess whether the overproduction of NO in AN can affect NO level in exhaled air. MATERIALS AND METHODS: E...

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Detalles Bibliográficos
Autores principales: Oświęcimska, Joanna, Ziora, Katarzyna, Ziora, Dariusz, Machura, Edyta, Smerdziński, Sebastian, Pyś-Spychała, Magdalena, Kasperski, Jacek, Zamłyński, Jacek, Kasperska-Zajac, Alicja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152618/
https://www.ncbi.nlm.nih.gov/pubmed/24276672
http://dx.doi.org/10.1007/s00787-013-0467-x
Descripción
Sumario:BACKGROUND: Nitric oxide (NO) is involved in eating behavior and inflammatory response. Moreover, there is evidence that NO production is altered in patients with anorexia nervosa (AN). AIM: To assess whether the overproduction of NO in AN can affect NO level in exhaled air. MATERIALS AND METHODS: Exhaled NO level was studied in 23 girls with AN and compared with that of healthy age- and gender-matched nonatopic controls. RESULTS: Exhaled NO levels were significantly higher in girls with AN compared with healthy age-matched controls. CONCLUSIONS: It appears that anorexia nervosa was accompanied by a higher level of exhaled NO, likely resulting from a systemic increase in NO production because of the severe catabolic state.

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