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Microphysical space of a liver sinusoid device enables simplified long-term maintenance of chimeric mouse-expanded human hepatocytes
While many advanced liver models support hepatic phenotypes necessary for drug and disease studies, these models are characterized by intricate features such as co-culture with one of more supporting cell types or advanced media perfusion systems. These systems have helped elucidate some of the crit...
Autores principales: | Maher, Steven P., Crouse, Richard B., Conway, Amy J., Bannister, Emilee C., Achyuta, Anil Kumar H., Clark, Amy Y., Sinatra, Francy L., Cuiffi, Joseph D., Adams, John H., Kyle, Dennis E., Saadi, Wajeeh M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152623/ https://www.ncbi.nlm.nih.gov/pubmed/24907052 http://dx.doi.org/10.1007/s10544-014-9877-x |
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