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Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage

Aneurysmal subarachnoid hemorrhage is associated with high mortality. Understanding of the underlying pathophysiology is important as early intervention can improve outcome. Increasing age, altered sensorium and poor Hunt and Hess grade are independent predictors of adverse outcome. Early operative...

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Autores principales: Kundra, Sandeep, Mahendru, Vidhi, Gupta, Vishnu, Choudhary, Ashwani Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152670/
https://www.ncbi.nlm.nih.gov/pubmed/25190938
http://dx.doi.org/10.4103/0970-9185.137261
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author Kundra, Sandeep
Mahendru, Vidhi
Gupta, Vishnu
Choudhary, Ashwani Kumar
author_facet Kundra, Sandeep
Mahendru, Vidhi
Gupta, Vishnu
Choudhary, Ashwani Kumar
author_sort Kundra, Sandeep
collection PubMed
description Aneurysmal subarachnoid hemorrhage is associated with high mortality. Understanding of the underlying pathophysiology is important as early intervention can improve outcome. Increasing age, altered sensorium and poor Hunt and Hess grade are independent predictors of adverse outcome. Early operative interventions imposes an onus on anesthesiologists to provide brain relaxation. Coiling and clipping are the two treatment options with increasing trends toward coiling. Intraoperatively, tight control of blood pressure and adequate brain relaxation is desirable, so that accidental aneurysm rupture can be averted. Patients with poor grades tolerate higher blood pressures, but are prone to ischemia whereas patients with lower grades tolerate lower blood pressure, but are prone to aneurysm rupture if blood pressure increases. Patients with Hunt and Hess Grade I or II with uneventful intraoperative course are extubated in operation theater, whereas, higher grades are kept electively ventilated. Postoperative management includes attention toward fluid status and early management of vasospasm.
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spelling pubmed-41526702014-09-04 Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage Kundra, Sandeep Mahendru, Vidhi Gupta, Vishnu Choudhary, Ashwani Kumar J Anaesthesiol Clin Pharmacol Review Article Aneurysmal subarachnoid hemorrhage is associated with high mortality. Understanding of the underlying pathophysiology is important as early intervention can improve outcome. Increasing age, altered sensorium and poor Hunt and Hess grade are independent predictors of adverse outcome. Early operative interventions imposes an onus on anesthesiologists to provide brain relaxation. Coiling and clipping are the two treatment options with increasing trends toward coiling. Intraoperatively, tight control of blood pressure and adequate brain relaxation is desirable, so that accidental aneurysm rupture can be averted. Patients with poor grades tolerate higher blood pressures, but are prone to ischemia whereas patients with lower grades tolerate lower blood pressure, but are prone to aneurysm rupture if blood pressure increases. Patients with Hunt and Hess Grade I or II with uneventful intraoperative course are extubated in operation theater, whereas, higher grades are kept electively ventilated. Postoperative management includes attention toward fluid status and early management of vasospasm. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4152670/ /pubmed/25190938 http://dx.doi.org/10.4103/0970-9185.137261 Text en Copyright: © Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kundra, Sandeep
Mahendru, Vidhi
Gupta, Vishnu
Choudhary, Ashwani Kumar
Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage
title Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage
title_full Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage
title_fullStr Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage
title_full_unstemmed Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage
title_short Principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage
title_sort principles of neuroanesthesia in aneurysmal subarachnoid hemorrhage
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152670/
https://www.ncbi.nlm.nih.gov/pubmed/25190938
http://dx.doi.org/10.4103/0970-9185.137261
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