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Choroidal Excavation in Vogt-Koyanagi-Harada Disease
PURPOSE: To report a case of choroidal excavation accompanied by Vogt-Koyanagi-Harada disease (VKH). METHODS: A 54-year-old Japanese woman who was complaining of bilateral blurring of vision associated with headache underwent optical coherence tomography (OCT), fluorescein angiography, and indocyani...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152928/ https://www.ncbi.nlm.nih.gov/pubmed/25202266 http://dx.doi.org/10.1159/000365441 |
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author | Hashida, Noriyasu Fok, Andrew Nishida, Kohji |
author_facet | Hashida, Noriyasu Fok, Andrew Nishida, Kohji |
author_sort | Hashida, Noriyasu |
collection | PubMed |
description | PURPOSE: To report a case of choroidal excavation accompanied by Vogt-Koyanagi-Harada disease (VKH). METHODS: A 54-year-old Japanese woman who was complaining of bilateral blurring of vision associated with headache underwent optical coherence tomography (OCT), fluorescein angiography, and indocyanine green angiography as well as a routine ophthalmological examination. RESULTS: Fundoscopy showed papilloedema and serous retinal detachment in both eyes. Fluorescein angiography detected bilateral multifocal leakage with pooling of dye in the subretinal space. Indocyanine green angiography showed patches of hyperfluorescence and hypofluorescent spots bilaterally. A diagnosis of VKH was reached soon afterwards. OCT of the left eye revealed the presence of a unilateral choroidal excavation under the fovea and subretinal fibrin over the site of the excavation. Treatment successfully resolved VKH symptoms with gradual resolution of subretinal fibrin and fluid; however, the choroidal excavation remained. CONCLUSIONS: This case is the first report of choroidal excavation associated with VKH. Our results suggest that choroidal excavation can be induced by choroidal inflammation caused by VKH. |
format | Online Article Text |
id | pubmed-4152928 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-41529282014-09-08 Choroidal Excavation in Vogt-Koyanagi-Harada Disease Hashida, Noriyasu Fok, Andrew Nishida, Kohji Case Rep Ophthalmol Published online: July, 2014 PURPOSE: To report a case of choroidal excavation accompanied by Vogt-Koyanagi-Harada disease (VKH). METHODS: A 54-year-old Japanese woman who was complaining of bilateral blurring of vision associated with headache underwent optical coherence tomography (OCT), fluorescein angiography, and indocyanine green angiography as well as a routine ophthalmological examination. RESULTS: Fundoscopy showed papilloedema and serous retinal detachment in both eyes. Fluorescein angiography detected bilateral multifocal leakage with pooling of dye in the subretinal space. Indocyanine green angiography showed patches of hyperfluorescence and hypofluorescent spots bilaterally. A diagnosis of VKH was reached soon afterwards. OCT of the left eye revealed the presence of a unilateral choroidal excavation under the fovea and subretinal fibrin over the site of the excavation. Treatment successfully resolved VKH symptoms with gradual resolution of subretinal fibrin and fluid; however, the choroidal excavation remained. CONCLUSIONS: This case is the first report of choroidal excavation associated with VKH. Our results suggest that choroidal excavation can be induced by choroidal inflammation caused by VKH. S. Karger AG 2014-07-16 /pmc/articles/PMC4152928/ /pubmed/25202266 http://dx.doi.org/10.1159/000365441 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published online: July, 2014 Hashida, Noriyasu Fok, Andrew Nishida, Kohji Choroidal Excavation in Vogt-Koyanagi-Harada Disease |
title | Choroidal Excavation in Vogt-Koyanagi-Harada Disease |
title_full | Choroidal Excavation in Vogt-Koyanagi-Harada Disease |
title_fullStr | Choroidal Excavation in Vogt-Koyanagi-Harada Disease |
title_full_unstemmed | Choroidal Excavation in Vogt-Koyanagi-Harada Disease |
title_short | Choroidal Excavation in Vogt-Koyanagi-Harada Disease |
title_sort | choroidal excavation in vogt-koyanagi-harada disease |
topic | Published online: July, 2014 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152928/ https://www.ncbi.nlm.nih.gov/pubmed/25202266 http://dx.doi.org/10.1159/000365441 |
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