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Monitoring of Occupational Exposure of Mild Steel Welders to Ozone and Nitrogen Oxides

BACKGROUND: Metal Inert Gas (MIG) welding and Tungsten Inert Gas (TIG) welding are widely used for mild steel segments in basic metal industries. Pulmonary problems such as asthma, pulmonary inflammation, hyper-responsiveness of airways and higher susceptibility to infections are reported as the res...

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Autores principales: Azari, Mansour R., Esmaeilzadeh, Morteza, Mehrabi, Yadollah, Salehpour, Sousan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Research Institute of Tuberculosis and Lung Disease 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153171/
https://www.ncbi.nlm.nih.gov/pubmed/25191389
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author Azari, Mansour R.
Esmaeilzadeh, Morteza
Mehrabi, Yadollah
Salehpour, Sousan
author_facet Azari, Mansour R.
Esmaeilzadeh, Morteza
Mehrabi, Yadollah
Salehpour, Sousan
author_sort Azari, Mansour R.
collection PubMed
description BACKGROUND: Metal Inert Gas (MIG) welding and Tungsten Inert Gas (TIG) welding are widely used for mild steel segments in basic metal industries. Pulmonary problems such as asthma, pulmonary inflammation, hyper-responsiveness of airways and higher susceptibility to infections are reported as the result of occupational exposure of welders to ozone and nitrogen oxides. Potent oxidizing agents like ozone and nitrogen oxides are also reported to be a precursor for respiratory problems and cause lipid peroxidation of membranes. MATERIALS AND METHODS: A total of 43 nonsmoking MIG and TIG welders and 41 nonsmoking workers without appreciable exposure to any chemicals as the control population were chosen to participate in this study. Occupational exposure to ozone was monitored according to the validated methods. Malondialdehyde (MDA) of blood serum as a biomarker for lipid peroxidation was analyzed using Reverse Phase High Performance Liquid Chromatography. Data obtained from this study were analyzed using t-test, Pearson's correlation coefficient and multiple regression analysis. RESULTS: A total of 88.4% and 74.4% of welders had exposure to ozone and nitrogen dioxide higher than the permissible limit of occupational exposure, respectively. Generally, exposure of MIG welders to ozone was significantly higher than TIG welders (P = 0.006). However, exposure to nitrogen dioxide gas was comparable in both groups. Serum MDA of welders was significantly higher than that of the control group (P = 0.001). A significant correlation was detected between ozone exposure and level of serum malondialdehyde. Such correlation was not observed for nitrogen dioxide exposure. CONCLUSION: Considering the high exposure of welders to ozone and nitrogen dioxide, and higher level of serum malondialdehyde in them compared to controls, risk management is recommended for this group of workers.
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spelling pubmed-41531712014-09-04 Monitoring of Occupational Exposure of Mild Steel Welders to Ozone and Nitrogen Oxides Azari, Mansour R. Esmaeilzadeh, Morteza Mehrabi, Yadollah Salehpour, Sousan Tanaffos Original Article BACKGROUND: Metal Inert Gas (MIG) welding and Tungsten Inert Gas (TIG) welding are widely used for mild steel segments in basic metal industries. Pulmonary problems such as asthma, pulmonary inflammation, hyper-responsiveness of airways and higher susceptibility to infections are reported as the result of occupational exposure of welders to ozone and nitrogen oxides. Potent oxidizing agents like ozone and nitrogen oxides are also reported to be a precursor for respiratory problems and cause lipid peroxidation of membranes. MATERIALS AND METHODS: A total of 43 nonsmoking MIG and TIG welders and 41 nonsmoking workers without appreciable exposure to any chemicals as the control population were chosen to participate in this study. Occupational exposure to ozone was monitored according to the validated methods. Malondialdehyde (MDA) of blood serum as a biomarker for lipid peroxidation was analyzed using Reverse Phase High Performance Liquid Chromatography. Data obtained from this study were analyzed using t-test, Pearson's correlation coefficient and multiple regression analysis. RESULTS: A total of 88.4% and 74.4% of welders had exposure to ozone and nitrogen dioxide higher than the permissible limit of occupational exposure, respectively. Generally, exposure of MIG welders to ozone was significantly higher than TIG welders (P = 0.006). However, exposure to nitrogen dioxide gas was comparable in both groups. Serum MDA of welders was significantly higher than that of the control group (P = 0.001). A significant correlation was detected between ozone exposure and level of serum malondialdehyde. Such correlation was not observed for nitrogen dioxide exposure. CONCLUSION: Considering the high exposure of welders to ozone and nitrogen dioxide, and higher level of serum malondialdehyde in them compared to controls, risk management is recommended for this group of workers. National Research Institute of Tuberculosis and Lung Disease 2011 /pmc/articles/PMC4153171/ /pubmed/25191389 Text en Copyright © 2011 National Research Institute of Tuberculosis and Lung Disease http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Azari, Mansour R.
Esmaeilzadeh, Morteza
Mehrabi, Yadollah
Salehpour, Sousan
Monitoring of Occupational Exposure of Mild Steel Welders to Ozone and Nitrogen Oxides
title Monitoring of Occupational Exposure of Mild Steel Welders to Ozone and Nitrogen Oxides
title_full Monitoring of Occupational Exposure of Mild Steel Welders to Ozone and Nitrogen Oxides
title_fullStr Monitoring of Occupational Exposure of Mild Steel Welders to Ozone and Nitrogen Oxides
title_full_unstemmed Monitoring of Occupational Exposure of Mild Steel Welders to Ozone and Nitrogen Oxides
title_short Monitoring of Occupational Exposure of Mild Steel Welders to Ozone and Nitrogen Oxides
title_sort monitoring of occupational exposure of mild steel welders to ozone and nitrogen oxides
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153171/
https://www.ncbi.nlm.nih.gov/pubmed/25191389
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