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Thoracic Imaging Findings of Collagen Vascular Diseases: A CT Study

BACKGROUND: Collagen vascular diseases (CVDs) are well known causes of pulmonary involvement, leading to significant morbidity. The purpose of this study was to identify several thoracic computed tomographic findings of CVDs. MATERIALS AND METHODS: The study included 56 patients (15 males and 41 fem...

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Autores principales: Karam, Mehrdad Bakhshayesh, Peivareh, Hamideh, Mosadegh, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Research Institute of Tuberculosis and Lung Disease 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153274/
https://www.ncbi.nlm.nih.gov/pubmed/25191493
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author Karam, Mehrdad Bakhshayesh
Peivareh, Hamideh
Mosadegh, Leila
author_facet Karam, Mehrdad Bakhshayesh
Peivareh, Hamideh
Mosadegh, Leila
author_sort Karam, Mehrdad Bakhshayesh
collection PubMed
description BACKGROUND: Collagen vascular diseases (CVDs) are well known causes of pulmonary involvement, leading to significant morbidity. The purpose of this study was to identify several thoracic computed tomographic findings of CVDs. MATERIALS AND METHODS: The study included 56 patients (15 males and 41 females) with histopathologically and clinically proven CVDs who were identified retrospectively. The presence, extent and distribution of various CT findings were evaluated by a radiologist. RESULTS: Lung parenchyma (96.4%) was the most common area of involvement. The lower lobes (89.2%) were the most frequent sites of involvement. The predominant CT patterns were reticulation (55.3%), peripheral subpleural interlobular septal thickening (51.7%) and ground glass opacity (50%). The most common histopathological findings according to CT features were obliterative bronchiolitis (OB, 44.6%) and non-specific interstitial pneumonia (NSIP, 33.9%). Usual interstitial pneumonia was seen in 12.5% and organizing pneumonia in 26.7% of patients. CONCLUSION: A combination of reticular pattern, peripheral subpleural interlobular septal thickening and ground glass opacity is seen in the majority of patients with CVDs. The results indicate that OB is more prevalent than what has been reported in previous studies. The CT patterns of pulmonary fibrosis are similar to those in most other studies.
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spelling pubmed-41532742014-09-04 Thoracic Imaging Findings of Collagen Vascular Diseases: A CT Study Karam, Mehrdad Bakhshayesh Peivareh, Hamideh Mosadegh, Leila Tanaffos Original Article BACKGROUND: Collagen vascular diseases (CVDs) are well known causes of pulmonary involvement, leading to significant morbidity. The purpose of this study was to identify several thoracic computed tomographic findings of CVDs. MATERIALS AND METHODS: The study included 56 patients (15 males and 41 females) with histopathologically and clinically proven CVDs who were identified retrospectively. The presence, extent and distribution of various CT findings were evaluated by a radiologist. RESULTS: Lung parenchyma (96.4%) was the most common area of involvement. The lower lobes (89.2%) were the most frequent sites of involvement. The predominant CT patterns were reticulation (55.3%), peripheral subpleural interlobular septal thickening (51.7%) and ground glass opacity (50%). The most common histopathological findings according to CT features were obliterative bronchiolitis (OB, 44.6%) and non-specific interstitial pneumonia (NSIP, 33.9%). Usual interstitial pneumonia was seen in 12.5% and organizing pneumonia in 26.7% of patients. CONCLUSION: A combination of reticular pattern, peripheral subpleural interlobular septal thickening and ground glass opacity is seen in the majority of patients with CVDs. The results indicate that OB is more prevalent than what has been reported in previous studies. The CT patterns of pulmonary fibrosis are similar to those in most other studies. National Research Institute of Tuberculosis and Lung Disease 2014 /pmc/articles/PMC4153274/ /pubmed/25191493 Text en Copyright © 2014 National Research Institute of Tuberculosis and Lung Disease http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Karam, Mehrdad Bakhshayesh
Peivareh, Hamideh
Mosadegh, Leila
Thoracic Imaging Findings of Collagen Vascular Diseases: A CT Study
title Thoracic Imaging Findings of Collagen Vascular Diseases: A CT Study
title_full Thoracic Imaging Findings of Collagen Vascular Diseases: A CT Study
title_fullStr Thoracic Imaging Findings of Collagen Vascular Diseases: A CT Study
title_full_unstemmed Thoracic Imaging Findings of Collagen Vascular Diseases: A CT Study
title_short Thoracic Imaging Findings of Collagen Vascular Diseases: A CT Study
title_sort thoracic imaging findings of collagen vascular diseases: a ct study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153274/
https://www.ncbi.nlm.nih.gov/pubmed/25191493
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