Cargando…

Keratoconus is associated with increased copy number of mitochondrial DNA

PURPOSE: To investigate the possible association of oxidative stress with keratoconus (KC), we estimated the changes in relative mitochondrial DNA (mtDNA) content. METHODS: The study included 119 patients with KC and 208 controls matched for gender, ethnicity, and systemic disease status. We selecte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abu-Amero, Khaled. K., Kondkar, Altaf A., Azad, Taif Anwar, Sultan, Tahira, Kalantan, Hatem, Al-Muammar, Abdulrahman M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153421/ https://www.ncbi.nlm.nih.gov/pubmed/25221426

Ejemplares similares

High-resolution analysis of DNA copy number alterations in patients with isolated sporadic keratoconus
por: Abu-Amero, Khaled K., et al.
Publicado: (2011)

Polymorphism rs13334190 in zinc finger protein 469 (ZNF469) is not a risk factor for keratoconus in a Saudi cohort
por: Kalantan, Hatem, et al.
Publicado: (2017)

Genetics of Keratoconus: Where Do We Stand?
por: Abu-Amero, Khaled K., et al.
Publicado: (2014)

Analysis of the VSX1 gene in keratoconus patients from Saudi Arabia
por: Abu-Amero, Khaled K., et al.
Publicado: (2011)

Lack of association between polymorphism rs540782 and primary open angle glaucoma in Saudi patients
por: Kondkar, Altaf A., et al.
Publicado: (2017)

Association of increased levels of plasma tumor necrosis factor alpha with primary open-angle glaucoma
por: Kondkar, Altaf A, et al.
Publicado: (2018)

Elevated levels of plasma tumor necrosis factor alpha in patients with pseudoexfoliation glaucoma
por: Kondkar, Altaf A, et al.
Publicado: (2018)

Polymorphism rs547984 on human chromosome 1q43 is not associated with primary open angle glaucoma in a Saudi cohort
por: Azad, Taif A., et al.
Publicado: (2017)

Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort
por: Kondkar, Altaf A., et al.
Publicado: (2018)

Polymorphisms rs693421 and rs2499601 at locus 1q43 and their haplotypes are not associated with primary open-angle glaucoma: a case–control study
por: Kondkar, Altaf A., et al.
Publicado: (2019)

Lack of Association between Variant rs7916697 in ATOH7 and Primary Open Angle Glaucoma in a Saudi Cohort
por: Kondkar, Altaf A., et al.
Publicado: (2018)

Association of total antioxidants level with glaucoma type and severity
por: Mousa, Ahmed, et al.
Publicado: (2015)

Polymorphism rs7555523 in transmembrane and coiled-coil domain 1 (TMCO1) is not a risk factor for primary open angle glaucoma in a Saudi cohort
por: Kondkar, Altaf A., et al.
Publicado: (2016)

Analysis of CYP1B1 sequence alterations in patients with primary open-angle glaucoma of Saudi origin
por: Abu-Amero, Khaled K, et al.
Publicado: (2018)

Increased Plasma Levels of 8-Hydroxy-2′-deoxyguanosine (8-OHdG) in Patients with Pseudoexfoliation Glaucoma
por: Kondkar, Altaf A., et al.
Publicado: (2019)

A catalase promoter variant rs1001179 is associated with visual acuity but not with primary angle closure glaucoma in Saudi patients
por: Abu-Amero, Khaled K, et al.
Publicado: (2013)

Total antioxidant level is correlated with intra-ocular pressure in patients with primary angle closure glaucoma
por: Abu-Amero, Khaled K, et al.
Publicado: (2014)

Screening of the Seed Region of MIR184 in Keratoconus Patients from Saudi Arabia
por: Abu-Amero, Khaled K., et al.
Publicado: (2015)

Utility of Circulating MicroRNAs as Clinical Biomarkers for Cardiovascular Diseases
por: Kondkar, Altaf A., et al.
Publicado: (2015)

Case-control association between CCT-associated variants and keratoconus in a Saudi Arabian population
por: Abu-Amero, Khaled K., et al.
Publicado: (2015)

Association analysis of polymorphisms rs12997 in ACVR1 and rs1043784 in BMP6 genes involved in bone morphogenic protein signaling pathway in primary angle-closure and pseudoexfoliation glaucoma patients of Saudi origin
por: Kondkar, Altaf A., et al.
Publicado: (2020)

Association of endothelial nitric oxide synthase (NOS3) gene polymorphisms with primary open-angle glaucoma in a Saudi cohort
por: Kondkar, Altaf A., et al.
Publicado: (2020)

Elevated Plasma Level of 8-Hydroxy-2′-deoxyguanosine Is Associated with Primary Open-Angle Glaucoma
por: Kondkar, Altaf A., et al.
Publicado: (2020)

An Updated Review on the Genetics of Primary Open Angle Glaucoma
por: Abu-Amero, Khaled, et al.
Publicado: (2015)

Unilateral keratoconus associated with iridocorneal endothelial syndrome: Case report
por: Kalantan, Hatem A.
Publicado: (2023)

Resveratrol and Ophthalmic Diseases
por: Abu-Amero, Khaled K., et al.
Publicado: (2016)

A microdeletion in the GRHL2 Gene in two unrelated patients with congenital fibrosis of the extra ocular muscles
por: Abu-Amero, Khaled K., et al.
Publicado: (2017)

Evaluation of ABCA1 and FNDC3B Gene Polymorphisms Associated With Pseudoexfoliation Glaucoma and Primary Angle-Closure Glaucoma in a Saudi Cohort
por: Kondkar, Altaf A., et al.
Publicado: (2022)

The 3’ UTR polymorphisms rs3742330 in DICER1 and rs10719 in DROSHA genes are not associated with primary open-angle and angle-closure glaucoma: As case-control study
por: Kondkar, Altaf A., et al.
Publicado: (2023)

Lack of Association of Polymorphism Located Upstream of ABCA1 (rs2472493), in FNDC3B (rs7636836), and Near ANKRD55–MAP3K1 Genes (rs61275591) in Primary Open-Angle Glaucoma Patients of Saudi Origin
por: Kondkar, Altaf A., et al.
Publicado: (2023)

A novel mutation in ornithine transcarbamylase gene causing mild intermittent hyperammonemia
por: Mohamed, Sarar, et al.
Publicado: (2015)

Sirtuins Expression and Their Role in Retinal Diseases
por: Balaiya, Sankarathi, et al.
Publicado: (2017)

Lack of Association Between Polymorphisms in TXNRD2 and LMX1B and Primary Open-Angle Glaucoma in a Saudi Cohort
por: Kondkar, Altaf A., et al.
Publicado: (2021)

Polymorphism rs3742330 in microRNA Biogenesis Gene DICER1 Is Associated with Pseudoexfoliation Glaucoma in Saudi Cohort
por: Kondkar, Altaf A., et al.
Publicado: (2022)

Comparison of Visual, Refractive and Topographic Keratometry Outcomes of Intacs and Intacs SK in Mild to Moderate Keratoconus Eyes
por: Al Muammar, Abdulrahman
Publicado: (2015)

Decreased total antioxidants status in the plasma of patients with pseudoexfoliation glaucoma
por: Abu-Amero, Khaled K., et al.
Publicado: (2011)

Lack of association of SNP rs4236601 near CAV1 and CAV2 with POAG in a Saudi cohort
por: Abu-Amero, Khaled K., et al.
Publicado: (2012)

Chromosome 6 microdeletion in a patient with syndromic congenital cranial dysinnervation disorder
por: Abu-Amero, Khaled K., et al.
Publicado: (2016)

High-resolution analysis of DNA copy number alterations in patients with primary open-angle glaucoma
por: Abu-Amero, Khaled K., et al.
Publicado: (2009)

Unaltered myocilin expression in the blood of primary open angle glaucoma patients
por: Abu-Amero, Khaled K., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_vvml8li74v5nulhar300buasa1