Reflux esophagitis in war-related sulfur mustard lung disease

Background Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago. Methods: One hundred two veterans with dysp...

Descripción completa

Detalles Bibliográficos
Autores principales: Roushan, Nader, Zali, Fateme, Abtahi, Hamidreza, Asadi, Mehrnaz, Taslimi, Reza, Aletaha, Najme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iran University of Medical Sciences 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153531/
https://www.ncbi.nlm.nih.gov/pubmed/25250271
_version_ 1782333295344746496
author Roushan, Nader
Zali, Fateme
Abtahi, Hamidreza
Asadi, Mehrnaz
Taslimi, Reza
Aletaha, Najme
author_facet Roushan, Nader
Zali, Fateme
Abtahi, Hamidreza
Asadi, Mehrnaz
Taslimi, Reza
Aletaha, Najme
author_sort Roushan, Nader
collection PubMed
description Background Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago. Methods: One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastroduodenoscopy. Of them, 52 cases had been exposed to SM and had chronic mustard lung disease. Controls included 50 veterans without SM exposure. Esophagitis was defined according to standard criteria. Results: 81.6% of cases and 70.6% of controls had heart burn and/or regurgitation (p= 0.224). Esophagitis was seen in 40% of cases and 26.5% of controls (p= 0.155). Conclusion: Based on our findings, SM exposure seems not to be associated with increased esophagitis.
format Online
Article
Text
id pubmed-4153531
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Iran University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-41535312014-09-23 Reflux esophagitis in war-related sulfur mustard lung disease Roushan, Nader Zali, Fateme Abtahi, Hamidreza Asadi, Mehrnaz Taslimi, Reza Aletaha, Najme Med J Islam Repub Iran Original Article Background Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago. Methods: One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastroduodenoscopy. Of them, 52 cases had been exposed to SM and had chronic mustard lung disease. Controls included 50 veterans without SM exposure. Esophagitis was defined according to standard criteria. Results: 81.6% of cases and 70.6% of controls had heart burn and/or regurgitation (p= 0.224). Esophagitis was seen in 40% of cases and 26.5% of controls (p= 0.155). Conclusion: Based on our findings, SM exposure seems not to be associated with increased esophagitis. Iran University of Medical Sciences 2014-05-07 /pmc/articles/PMC4153531/ /pubmed/25250271 Text en © 2014 Iran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Roushan, Nader
Zali, Fateme
Abtahi, Hamidreza
Asadi, Mehrnaz
Taslimi, Reza
Aletaha, Najme
Reflux esophagitis in war-related sulfur mustard lung disease
title Reflux esophagitis in war-related sulfur mustard lung disease
title_full Reflux esophagitis in war-related sulfur mustard lung disease
title_fullStr Reflux esophagitis in war-related sulfur mustard lung disease
title_full_unstemmed Reflux esophagitis in war-related sulfur mustard lung disease
title_short Reflux esophagitis in war-related sulfur mustard lung disease
title_sort reflux esophagitis in war-related sulfur mustard lung disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153531/
https://www.ncbi.nlm.nih.gov/pubmed/25250271
work_keys_str_mv AT roushannader refluxesophagitisinwarrelatedsulfurmustardlungdisease
AT zalifateme refluxesophagitisinwarrelatedsulfurmustardlungdisease
AT abtahihamidreza refluxesophagitisinwarrelatedsulfurmustardlungdisease
AT asadimehrnaz refluxesophagitisinwarrelatedsulfurmustardlungdisease
AT taslimireza refluxesophagitisinwarrelatedsulfurmustardlungdisease
AT aletahanajme refluxesophagitisinwarrelatedsulfurmustardlungdisease

Ejemplares similares