Subacute Intranasal Administration of Tissue Plasminogen Activator Promotes Neuroplasticity and Improves Functional Recovery following Traumatic Brain Injury in Rats

Traumatic brain injury (TBI) is a major cause of death and long-term disability worldwide. To date, there are no effective pharmacological treatments for TBI. Recombinant human tissue plasminogen activator (tPA) is the effective drug for the treatment of acute ischemic stroke. In addition to its thr...

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Detalles Bibliográficos
Autores principales: Meng, Yuling, Chopp, Michael, Zhang, Yanlu, Liu, Zhongwu, An, Aaron, Mahmood, Asim, Xiong, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153585/
https://www.ncbi.nlm.nih.gov/pubmed/25184365
http://dx.doi.org/10.1371/journal.pone.0106238

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