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Nogo Receptor Inhibition Enhances Functional Recovery following Lysolecithin-Induced Demyelination in Mouse Optic Chiasm

BACKGROUND: Inhibitory factors have been implicated in the failure of remyelination in demyelinating diseases. Myelin associated inhibitors act through a common receptor called Nogo receptor (NgR) that plays critical inhibitory roles in CNS plasticity. Here we investigated the effects of abrogating...

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Detalles Bibliográficos
Autores principales: Pourabdolhossein, Fereshteh, Mozafari, Sabah, Morvan-Dubois, Ghislaine, Mirnajafi-Zadeh, Javad, Lopez-Juarez, Alejandra, Pierre-Simons, Jacqueline, Demeneix, Barbara A., Javan, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153612/
https://www.ncbi.nlm.nih.gov/pubmed/25184636
http://dx.doi.org/10.1371/journal.pone.0106378